Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase - Wikidata - awgldk - TriplyDB

Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase

Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase

http://www.wikidata.org/entity/Q27480929

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Apoptosis in animal models of virus-induced disease Multi-organ lesions in suckling mice infected with SARS-associated mammalian reovirus linked with apoptosis induced by viral proteins μ1 and σ1 Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain.Development of an intracellularly acting inhibitory peptide selective for PKN.Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain Bid regulates the pathogenesis of neurotropic reovirus.Gene expression in the brain during reovirus encephalitis.Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.Caspase-3 activation is required for reovirus-induced encephalitis in vivo.A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition.The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis JNK1 Derived from Orange-Spotted Grouper, Epinephelus coioides, Involving in the Evasion and Infection of Singapore Grouper Iridovirus (SGIV).Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis.Reovirus activates a caspase-independent cell death pathway.JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection.Fas-mediated apoptotic signaling in the mouse brain following reovirus infection Apoptosis induced by mammalian reovirus is beta interferon (IFN) independent and enhanced by IFN regulatory factor 3- and NF-κB-dependent expression of Noxa.Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiency.

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Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase

http://www.wikidata.org/entity/Q27480929

description

2007 nî lūn-bûn

@nan

2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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Novel Strategy for Treatment o ...... tor of c-Jun N-Terminal Kinase

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P1433

Journal of Virology

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Novel strategy for treatment o ...... tor of c-Jun N-terminal kinase

@en

P2093

Christophe Bonny

http://www.w3.org/2001/XMLSchema#string

J David Beckham

http://www.w3.org/2001/XMLSchema#string

Penny Clarke

http://www.w3.org/2001/XMLSchema#string

Robin J Goody

http://www.w3.org/2001/XMLSchema#string

P2860

Induction of inflammation by West Nile virus capsid through the caspase-9 apoptotic pathway

JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins

Mammalian MAP kinase signalling cascades

Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors.

Reovirus-induced G(2)/M cell cycle arrest requires sigma1s and occurs in the absence of apoptosis.

Induction of apoptosis by Sindbis virus occurs at cell entry and does not require virus replication.

Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun.

Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease.

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death.

Neurologic manifestations and outcome of West Nile virus infection.

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6984-6992

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scholarly article

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10.1128/JVI.00467-07

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13

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81

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Kenneth L. Tyler

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2007-05-02T00:00:00Z

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17475657

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1933289

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