DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus - Wikidata - awgldk - TriplyDB

DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus

DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus

http://www.wikidata.org/entity/Q27480946

about

Vaccines in development against West Nile virus RNA structures required for production of subgenomic flavivirus RNA A Novel Synthetic TLR-4 Agonist Adjuvant Increases the Protective Response to a Clinical-Stage West Nile Virus Vaccine Antigen in Multiple Formulations Rescue of the 1947 Zika Virus Prototype Strain with a Cytomegalovirus Promoter-Driven cDNA Clone A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice Resistance to Alpha/Beta Interferon Is a Determinant of West Nile Virus Replication Fitness and Virulence Translation of the Flavivirus Kunjin NS3 Gene in cis but Not Its RNA Sequence or Secondary Structure Is Essential for Efficient RNA Packaging Monoclonal Antibody-Based Competitive Enzyme-Linked Immunosorbent Assay for Detecting and Quantifying West Nile Virus-Neutralizing Antibodies in Horse Sera Complex adenovirus-mediated expression of West Nile virus C, PreM, E, and NS1 proteins induces both humoral and cellular immune responses.Production and characterization of vaccines based on flaviviruses defective in replication The relative contribution of antibody and CD8+ T cells to vaccine immunity against West Nile encephalitis virus Defining the levels of secreted non-structural protein NS1 after West Nile virus infection in cell culture and mice Plant-made vaccines against West Nile virus are potent, safe, and economically feasible The role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses.West Nile virus vaccines.Safety and immunogenicity of a delta inulin-adjuvanted inactivated Japanese encephalitis virus vaccine in pregnant mares and foals Current trends in West Nile virus vaccine development.Virulence determinants between New York 99 and Kunjin strains of West Nile virus Structure and function of the 3' terminal six nucleotides of the west nile virus genome in viral replication.Recent advancement in flavivirus vaccine development.West Nile virus: a growing concern?Characterization of virulent West Nile virus Kunjin strain, Australia, 2011.Protective immunity to Japanese encephalitis virus associated with anti-NS1 antibodies in a mouse model.Kunjin virus replicons: an RNA-based, non-cytopathic viral vector system for protein production, vaccine and gene therapy applications.Novel vaccine against Venezuelan equine encephalitis combines advantages of DNA immunization and a live attenuated vaccine Mimicking live flavivirus immunization with a noninfectious RNA vaccine.A novel bacterium-free method for generation of flavivirus infectious DNA by circular polymerase extension reaction allows accurate recapitulation of viral heterogeneity.A hydrogen peroxide-inactivated virus vaccine elicits humoral and cellular immunity and protects against lethal West Nile virus infection in aged mice.Molecular and immunological characterization of a DNA-launched yellow fever virus 17D infectious clone.The role of Australian mosquito species in the transmission of endemic and exotic West Nile virus strains.A review of vaccine approaches for West Nile virus.West Nile virus genome with glycosylated envelope protein and deletion of alpha helices 1, 2, and 4 in the capsid protein is noninfectious and efficiently secretes subviral particles.West Nile virus state of the art report of MALWEST Project.Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription.Vaccines and immunotherapeutics for the prevention and treatment of infections with West Nile virus.An Overview of Current Approaches Toward the Treatment and Prevention of West Nile Virus Infection.DNA-launched live-attenuated vaccines for biodefense applications.Pre-clinical development of a hydrogen peroxide-inactivated West Nile virus vaccine.A case of Murray Valley encephalitis in a 2-year-old Australian Stock Horse in south-east Queensland.Plasmid DNA launches live-attenuated Japanese encephalitis virus and elicits virus-neutralizing antibodies in BALB/c mice.

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P2860

DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus

http://www.wikidata.org/entity/Q27480946

description

2003 nî lūn-bûn

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2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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DNA vaccine coding for the ful ...... York strain of West Nile virus

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DNA vaccine coding for the ful ...... York strain of West Nile virus

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DNA vaccine coding for the ful ...... York strain of West Nile virus

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DNA vaccine coding for the ful ...... York strain of West Nile virus

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Proceedings of the National Academy of Sciences of the United States of America

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DNA vaccine coding for the ful ...... York strain of West Nile virus

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Debra J Nisbet

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Kim B Pham

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P2860

Glycosylation and antigenic variation among Kunjin virus isolates

trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells.

A single intramuscular injection of recombinant plasmid DNA induces protective immunity and prevents Japanese encephalitis in mice

Stable high-level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectors

West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assays.

Coupling between replication and packaging of flavivirus RNA: evidence derived from the use of DNA-based full-length cDNA clones of Kunjin virus

Kunjin virus replicon vaccine vectors induce protective CD8+ T-cell immunity.

Molecular and Functional Analyses of Kunjin Virus Infectious cDNA Clones Demonstrate the Essential Roles for NS2A in Virus Assembly and for a Nonconservative Residue in NS3 in RNA Replication

The Relationships between West Nile and Kunjin Viruses

Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States

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3294724

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10.1073/PNAS.1834270100

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18

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100

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Alexander A. Khromykh

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10613742

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12917491

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West Nile virus

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193583

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