High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome - Wikidata - awgldk - TriplyDB

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

http://www.wikidata.org/entity/Q27485454

about

Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling Adaptive immunity in the liver Programmed death-1/programmed death-L1 signaling pathway and its blockade in hepatitis C virus immunotherapy Immune responses to HCV and other hepatitis viruses Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer Impaired Hepatitis C Virus (HCV)-Specific Effector CD8+ T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8+ Memory T Cells Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C Structure and Interactions of the Human Programmed Cell Death 1 Receptor Innate and Adaptive Immune Regulation During Chronic Viral Infections Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function Programmed Death-1 expression on Epstein Barr virus specific CD8+ T cells varies by stage of infection, epitope specificity, and T-cell receptor usage Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis.Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection.Chronically inflamed livers up-regulate expression of inhibitory B7 family members.Maternal infection with Trypanosoma cruzi and congenital Chagas disease induce a trend to a type 1 polarization of infant immune responses to vaccines Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation.CD8(+) T-Cell Responses in Acute Hepatitis C Virus Infection.Protective immunity against hepatitis C: many shades of gray.Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells.CD4 T-cell help programs a change in CD8 T-cell function enabling effective long-term control of murine gammaherpesvirus 68: role of PD-1-PD-L1 interactions.Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin's lymphoma.T-cell dysfunction and inhibitory receptors in hepatitis C virus infection.EBV-specific CD8+ T cells from asymptomatic pediatric thoracic transplant patients carrying chronic high EBV loads display contrasting features: activated phenotype and exhausted function Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice.Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B.CD4 T Cells Mediate Both Positive and Negative Regulation of the Immune Response to HIV Infection: Complex Role of T Follicular Helper Cells and Regulatory T Cells in Pathogenesis Immune regulation in Chandipura virus infection: characterization of CD4+ T regulatory cells from infected mice.Coinfection with HIV-1 and HCV--a one-two punch.Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence.Spontaneous clearance of chronic hepatitis C virus infection is associated with appearance of neutralizing antibodies and reversal of T-cell exhaustion PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing CD39 Expression Identifies Terminally Exhausted CD8+ T Cells Update on hepatitis C virus-specific immunity IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma.

P2860

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P2860

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

http://www.wikidata.org/entity/Q27485454

description

2008 nî lūn-bûn

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2008 թուականի Մարտին հրատարակուած գիտական յօդուած

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2008 թվականի մարտին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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Journal of Virology

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Andrew Berical

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Arthur Y Kim

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Barbara G McGovern

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Brian E Nolan

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Cory McMahon

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Georg M Lauer

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Gordon Freeman

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Jenna Blum

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Laura L Reyor

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Lia Lewis-Ximenez

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P2860

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection

Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

Hepatitis C virus infection

Restoring function in exhausted CD8 T cells during chronic viral infection

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection.

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3154-60

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scholarly article

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2719109

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10.1128/JVI.02474-07

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6

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82

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Bruce D. Walker

Julian Schulze zur Wiesch

Raymond T Chung

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2008-03-01T00:00:00Z

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51392807

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18160439

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2258997

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