Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism
about
Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complexHepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathwayThe internal ribosome entry site (IRES) of hepatitis C virus visualized by electron microscopy.A cellular RNA-binding protein enhances internal ribosomal entry site-dependent translation through an interaction downstream of the hepatitis C virus polyprotein initiation codonA peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulationCrystal structure of the HCV IRES central domain reveals strategy for start-codon positioningInitiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type ITranslation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organizationTranslation of the F protein of hepatitis C virus is initiated at a non-AUG codon in a +1 reading frame relative to the polyproteinA hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIIdKinetics of initiating polypeptide elongation in an IRES-dependent systemChaperones in hepatitis C virus infectionHost-Targeting Agents to Prevent and Cure Hepatitis C Virus InfectionInhibitors of the Hepatitis C Virus Polymerase; Mode of Action and ResistanceHCVIVdb: The hepatitis-C IRES variation databaseInfluence of correct secondary and tertiary RNA folding on the binding of cellular factors to the HCV IRESA phylogenetically conserved stem-loop structure at the 5' border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation.Translation initiation at the CUU codon is mediated by the internal ribosome entry site of an insect picorna-like virus in vitroPoliovirus/Hepatitis C virus (internal ribosomal entry site-core) chimeric viruses: improved growth properties through modification of a proteolytic cleavage site and requirement for core RNA sequences but not for core-related polypeptides.Alterations to both the primary and predicted secondary structure of stem-loop IIIc of the hepatitis C virus 1b 5' untranslated region (5'UTR) lead to mutants severely defective in translation which cannot be complemented in trans by the wild-type 5Multiple enzymatic activities associated with recombinant NS3 protein of hepatitis C virusComplete genomic sequence of border disease virus, a pestivirus from sheep.A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element.Heterogeneous nuclear ribonucleoprotein L interacts with the 3' border of the internal ribosomal entry site of hepatitis C virusHepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding.Comparative analysis of translation efficiencies of hepatitis C virus 5' untranslated regions among intraindividual quasispecies present in chronic infection: opposite behaviors depending on cell typeMutational analysis of the GB virus B internal ribosome entry siteAn enzymatic footprinting analysis of the interaction of 40S ribosomal subunits with the internal ribosomal entry site of hepatitis C virusNatural variation in translational activities of the 5' nontranslated RNAs of hepatitis C virus genotypes 1a and 1b: evidence for a long-range RNA-RNA interaction outside of the internal ribosomal entry siteSpecific interaction between the hepatitis C virus NS5B RNA polymerase and the 3' end of the viral RNACore protein-coding sequence, but not core protein, modulates the efficiency of cap-independent translation directed by the internal ribosome entry site of hepatitis C virusCharacterization of cell lines carrying self-replicating hepatitis C virus RNAs.Mutations in Hepatitis C Virus RNAs Conferring Cell Culture AdaptationEfficient Translation Initiation Is Required for Replication of Bovine Viral Diarrhea Virus Subgenomic RepliconsEnhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations.Regulation of mRNA Translation and Cellular Signaling by Hepatitis C Virus Nonstructural Protein NS5ASequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.A peptide derived from RNA recognition motif 2 of human la protein binds to hepatitis C virus internal ribosome entry site, prevents ribosomal assembly, and inhibits internal initiation of translation.Hepatitis C virus internal ribosome entry site-dependent translation in Saccharomyces cerevisiae is independent of polypyrimidine tract-binding protein, poly(rC)-binding protein 2, and La proteinInhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs
P2860
Q24537657-15C7BDFF-AC00-48C4-A84B-8D462932C7DAQ24537844-7861CA60-3952-4B4F-8F86-CE30039E75A5Q24540019-611D52D1-4F7A-4C56-BCBC-310866C5B36EQ24563044-A9D72EC4-4CEB-420A-B840-87076E5B6037Q24600240-6C8C4BAA-9692-454B-9BC8-8905B75F93DAQ24630978-D4441C6B-BF1A-4042-BE41-D511B664B9F8Q24676039-60FB9E35-C4AE-474E-870F-DCFFD0F69116Q24681213-515FDC68-C36A-4154-96DA-3E09A6D5584CQ24795677-EE8BF7B7-BAA2-4D80-A51C-3F2A3F8FAAF4Q24802106-E6776A70-1A64-4B27-B2BA-8921EFEEF916Q26700123-A93AB87E-B549-43E5-B698-657256CB14EFQ26771251-2983FB62-5E71-44EC-8018-9DF9F8AD8E40Q26779128-CF8B864E-BD94-4DB3-B352-21DAB9BFCEA9Q26783056-4D565250-A047-4FE7-A472-067860C6DB32Q27468878-0C1D0D3B-0008-4896-A52A-BA35C23E5FA1Q27469319-C281D21A-BFA7-4F38-A985-8BAB7D15881CQ27469343-76EA39C6-25B8-4223-B476-2531FC5813A8Q27469344-69CAC76C-B3B5-4F66-ACA0-CE92EB3B3070Q27469345-8C9F6CC2-91A3-4AE0-94EE-9B18E3D532C4Q27469375-21F50C50-191B-49EB-A3AF-8121AACC2B5EQ27469559-9FC0C22A-4769-4375-A54C-F764A2419A63Q27469570-2A8C74A6-E69D-47A1-A8DE-976AECD78B9BQ27469576-92554F25-E06A-4F4C-81FB-C47DEAE98119Q27469579-3BD4FEB0-ED20-4C13-ADF3-B627FD06132FQ27469600-8D7B5A5B-1EA8-47E6-9D6B-53174163512DQ27469602-9D4A6934-3273-4AAC-A09B-F8DC250B6F89Q27469623-D52C79D4-67CE-4284-AB53-82E4C7BE8D08Q27469672-1EA90562-34F8-4F29-AD2C-EEDC441977B8Q27469708-DB1314C0-1659-4646-8D38-2AD4ADB3E021Q27469725-73AC6183-6881-4477-8968-49273C8D3B06Q27469759-E2E99D14-9350-4D19-A4B4-FD9CEBFBD6D7Q27469765-3FC236A0-18D7-46D0-8A48-AC20D8AF11E3Q27469769-B397B7DC-A6A6-4078-BBD4-7F714BB700B5Q27469787-3CF63763-2A2B-44C9-9B80-AD2C6B174517Q27469794-6F5BB13F-B72A-45D3-9231-9964414E310DQ27469918-30D15A4C-DED9-490A-B2EA-AD52F5E0C2FFQ27469999-402C798D-5EEE-4252-8B32-D225FC513ECFQ27470332-E870AA43-3949-4448-9671-5C3ECFB6BE52Q27470417-320D2231-6CDE-46DD-92B2-D610D5937296Q27472783-C52DB228-38C5-4871-B005-94FF336FBC45
P2860
Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Translation of human hepatitis ...... nal ribosome-binding mechanism
@ast
Translation of human hepatitis ...... nal ribosome-binding mechanism
@en
Translation of human hepatitis ...... nal ribosome-binding mechanism
@nl
type
label
Translation of human hepatitis ...... nal ribosome-binding mechanism
@ast
Translation of human hepatitis ...... nal ribosome-binding mechanism
@en
Translation of human hepatitis ...... nal ribosome-binding mechanism
@nl
prefLabel
Translation of human hepatitis ...... nal ribosome-binding mechanism
@ast
Translation of human hepatitis ...... nal ribosome-binding mechanism
@en
Translation of human hepatitis ...... nal ribosome-binding mechanism
@nl
P2093
P2860
P3181
P1433
P1476
Translation of human hepatitis ...... nal ribosome-binding mechanism
@en
P2093
P2860
P304
P3181
P577
1993-06-01T00:00:00Z