Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus
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A host YB-1 ribonucleoprotein complex is hijacked by hepatitis C virus for the control of NS3-dependent particle productionSignal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2The hepatitis C virus glycan shield and evasion of the humoral immune responseIdentification of a novel drug lead that inhibits HCV infection and cell-to-cell transmission by targeting the HCV E2 glycoproteinProduction of infectious HCV genotype 1b virus in cell culture using a novel Set of adaptive mutations(4R,6S)-2-Dihydromenisdaurilide is a Butenolide that Efficiently Inhibits Hepatitis C Virus EntryHepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutationIdentification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing AntibodiesTight Junction Proteins Claudin-1 and Occludin Control Hepatitis C Virus Entry and Are Downregulated during Infection To Prevent SuperinfectionDifferential Effects of Hepatitis C Virus JFH1 on Human Myeloid and Plasmacytoid Dendritic CellsMutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus InfectivityProduction of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing MutationsThe association of CD81 with tetraspanin-enriched microdomains is not essential for Hepatitis C virus entryHepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme ComplexesMutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particlesHepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor -Dependent Manner: a New Contributor to HCV-Induced Oxidative StressCD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cellsStearoyl-CoA desaturase inhibition blocks formation of hepatitis C virus-induced specialized membranesSingle strain isolation method for cell culture-adapted hepatitis C virus by end-point dilution and infection.Characterization of miR-122-independent propagation of HCV.Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolismNovel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studiesMutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription.Generation of a cell culture-adapted hepatitis C virus with longer half life at physiological temperature.Analysis of functional differences between hepatitis C virus NS5A of genotypes 1-7 in infectious cell culture systems.Role of N-linked glycans in the functions of hepatitis C virus envelope proteins incorporated into infectious virions.Identification of basic amino acids at the N-terminal end of the core protein that are crucial for hepatitis C virus infectivity.A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses.Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particlesReproduction in vitro of a quasispecies from a hepatitis C virus-infected patient and determination of factors that influence selection of a dominant species.Efficient culture adaptation of hepatitis C virus recombinants with genotype-specific core-NS2 by using previously identified mutations.Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry.Permissivity of primary human hepatocytes and different hepatoma cell lines to cell culture adapted hepatitis C virus.Efficient infectious cell culture systems of the hepatitis C virus (HCV) prototype strains HCV-1 and H77.Conserved GXXXG- and S/T-like motifs in the transmembrane domains of NS4B protein are required for hepatitis C virus replicationThe subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 proteinHepatitis C virus is primed by CD81 protein for low pH-dependent fusionHepatitis C virus and antiviral innate immunity: who wins at tug-of-war?A genetic interaction between the core and NS3 proteins of hepatitis C virus is essential for production of infectious virus
P2860
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P2860
Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@ast
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@en
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@nl
type
label
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@ast
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@en
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@nl
prefLabel
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@ast
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@en
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@nl
P2093
P2860
P3181
P356
P1476
Advantages of a single-cycle p ...... mutations of hepatitis C virus
@en
P2093
Jean-Christophe Meunier
Kristina Faulk
Robert H Purcell
Rodney S Russell
Ronald E Engle
Shingo Takikawa
Suzanne U Emerson
P2860
P304
P3181
P356
10.1073/PNAS.0800422105
P407
P50
P577
2008-03-18T00:00:00Z