The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket - Wikidata - awgldk - TriplyDB

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

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Replication of alphaviruses: a review on the entry process of alphaviruses into cells Incrimination of Aedes (Stegomyia) hensilli Farner as an epidemic vector of Chikungunya virus on Yap Island, Federated States of Micronesia, 2013 Mosquito Rasputin interacts with chikungunya virus nsP3 and determines the infection rate in Aedes albopictus Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2 Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity Alphavirus RNA synthesis and non-structural protein functions Differences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest Virus Chikungunya virus (CHIKV) inhibitors from natural sources: a medicinal chemistry perspective High-resolution functional mapping of the venezuelan equine encephalitis virus genome by insertional mutagenesis and massively parallel sequencing A structural and functional perspective of alphavirus replication and assembly Nuclear Magnetic Resonance Structure of the Nucleic Acid-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 3 The N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA Transcription Structural and functional insights into alphavirus polyprotein processing and pathogenesis Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence Chikungunya virus nsP3 blocks stress granule assembly by recruitment of G3BP into cytoplasmic foci.SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication Random codon re-encoding induces stable reduction of replicative fitness of Chikungunya virus in primate and mosquito cells Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region.Development of infectious cDNA clones of Salmonid alphavirus subtype 3.BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1)Replication cycle of chikungunya: a re-emerging arbovirus.Requirement for the amino-terminal domain of sindbis virus nsP4 during virus infection.Characterization of the interactions between the nucleoprotein and the phosphoprotein of Henipavirus Improving the soluble expression of recombinant proteins by randomly shuffling 5' and 3' coding-sequence ends.Dissection of amino-terminal functional domains of murine coronavirus nonstructural protein 3.Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein.New World and Old World Alphaviruses Have Evolved to Exploit Different Components of Stress Granules, FXR and G3BP Proteins, for Assembly of Viral Replication Complexes.Viral Macro Domains Reverse Protein ADP-Ribosylation.Alphavirus mutator variants present host-specific defects and attenuation in mammalian and insect models PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.Emergence and clinical insights into the pathology of Chikungunya virus infection.Reprogramming cellular events by poly(ADP-ribose)-binding proteins Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.The recognition and removal of cellular poly(ADP-ribose) signals.Analysis of chikungunya virus proteins reveals that non-structural proteins nsP2 and nsP3 exhibit RNA interference (RNAi) suppressor activity.Design and Validation of Novel Chikungunya Virus Protease Inhibitors.Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.Hypervariable domain of nonstructural protein nsP3 of Venezuelan equine encephalitis virus determines cell-specific mode of virus replication.Hypervariable domains of nsP3 proteins of New World and Old World alphaviruses mediate formation of distinct, virus-specific protein complexes.

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The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

http://www.wikidata.org/entity/Q27488798

description

2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

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article scientifique (publié 2009-07)

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articolo scientifico (pubblicato il 2009-07)

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artigo científico (publicado na 2009-07)

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artículu científicu espublizáu en 2009

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im Juli 2009 veröffentlichter wissenschaftlicher Artikel

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scientific article (publication date: July 2009)

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vedecký článok (publikovaný 2009-07)

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vetenskaplig artikel (publicerad på 2009-07)

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The Crystal Structures of Chik ...... erved Adenosine Binding Pocket

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Journal of Virology

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The Crystal Structures of Chik ...... erved Adenosine Binding Pocket

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Ernest A Gould

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Francois Ferron

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Naomi Forrester

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Nicolas Papageorgiou

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Saïd Jamal

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The macro domain is an ADP-ribose binding module

Evolutionary relationships and systematics of the alphaviruses.

Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains

SMART 5: domains in the context of genomes and networks

ATPase and GTPase activities associated with Semliki Forest virus nonstructural protein nsP2

Nuclear localization of Semliki Forest virus-specific nonstructural protein nsP2

The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A

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6534-45

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4166585

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10.1128/JVI.00189-09

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13

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83

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Xavier de Lamballerie

Hélène Dutartre

Alexander E Gorbalenya

Maarit Neuvonen

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2009-07-01T00:00:00Z

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19386706

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Chikungunya virus

crystal structure

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2698539

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