Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection
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Infection with MERS-CoV causes lethal pneumonia in the common marmosetExacerbated innate host response to SARS-CoV in aged non-human primatesLack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret modelThe role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis.Proteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.Pandemic Influenza A (H1N1) Virus Infection Increases Apoptosis and HIV-1 Replication in HIV-1 Infected Jurkat Cells.Increased viral loads and exacerbated innate host responses in aged macaques infected with the 2009 pandemic H1N1 influenza A virus.The application of genomics to emerging zoonotic viral diseasesSevere acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesisEscape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirusLung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor/c-Met signaling.Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaquesComparative pathogenesis and systems biology for biodefense virus vaccine development.The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis.Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.A chemokine gene expression signature derived from meta-analysis predicts the pathogenicity of viral respiratory infectionsT cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice.Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection.Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse modelEpithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques.Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology.A human lung xenograft mouse model of Nipah virus infection.Clinical outcome of henipavirus infection in hamsters is determined by the route and dose of infection.A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challengeAge-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice.Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease.Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections.A review of genetic methods and models for analysis of coronavirus-induced severe pneumonitis.Bugs in the system.The replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory cytokinesSevere acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses.Animal models in virus research: their utility and limitations.Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology.Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species.Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease.Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury.Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains.Prophylactic, therapeutic and immune enhancement effect of liposome-encapsulated PolyICLC on highly pathogenic H5N1 influenza infectionEvaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform
P2860
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P2860
Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@ast
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@en
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@nl
type
label
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@ast
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@en
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@nl
prefLabel
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@ast
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@en
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@nl
P2093
P2860
P50
P356
P1433
P1476
Early Upregulation of Acute Re ...... Syndrome Coronavirus Infection
@en
P2093
Barry Rockx
Gregory A Zornetzer
Judith van den Brand
Matthew D Dyer
Matthew Frieman
Sean Proll
Thomas H Teal
Timothy Sheahan
Tracey Baas
P2860
P304
P356
10.1128/JVI.00127-09
P577
2009-07-01T00:00:00Z