Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees
about
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.Hepatitis C virus proteinsStatus of hepatitis C virus vaccination: Recent updateGenetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine DesignConservation of the Conformation and Positive Charges of Hepatitis C Virus E2 Envelope Glycoprotein Hypervariable Region 1 Points to a Role in Cell AttachmentStimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymeraseBasic residues in hypervariable region 1 of hepatitis C virus envelope glycoprotein e2 contribute to virus entry.Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease.Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infectionMutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees.Complement-mediated enhancement of antibody function for neutralization of pseudotype virus containing hepatitis C virus E2 chimeric glycoproteinSignificance of Pretreatment Analysis of Hepatitis C Virus Genotype 1b Hypervariable Region 1 Sequences To Predict Antiviral OutcomeMonitoring of Hepatitis C Virus Quasispecies in Chronic Infection by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Mutation DetectionIn Vivo Study of the HC-TN Strain of Hepatitis C Virus Recovered from a Patient with Fulminant Hepatitis: RNA Transcripts of a Molecular Clone (pHC-TN) Are Infectious in Chimpanzees but Not in Huh7.5 CellsThe p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequencesPreviously Infected Chimpanzees Are Not Consistently Protected against Reinfection or Persistent Infection after Reexposure to the Identical Hepatitis C Virus StrainInternal Initiation Stimulates Production of p8 Minicore, a Member of a Newly Discovered Family of Hepatitis C Virus Core Protein IsoformsBlocking Hepatitis C Virus Infection with Recombinant Form of Envelope Protein 2 EctodomainThe Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the MoleculeIn vitro assay for neutralizing antibody to hepatitis C virus: Evidence for broadly conserved neutralization epitopesIdentification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2Production of infectious hepatitis C virus in tissue culture from a cloned viral genomeUnravelling hepatitis C virus replication from genome to functionHCV infection of the transplanted liver: changing CD81 and HVR1 variants immediately after liver transplantation.Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes.Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarinsThe entire core protein of HCV JFH1 is required for efficient formation of infectious JFH1 pseudoparticles.The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development.New therapeutic strategies for hepatitis C.Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralizationReproduction in vitro of a quasispecies from a hepatitis C virus-infected patient and determination of factors that influence selection of a dominant species.Meta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicates an importance for structural proteins.Mechanisms of hepatitis C virus infection.Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A.Three different functional microdomains in the hepatitis C virus hypervariable region 1 (HVR1) mediate entry and immune evasion.Underwhelming the immune response: effect of slow virus growth on CD8+-T-lymphocyte responses.Recent advances in our understanding of receptor binding, viral fusion and cell entry of hepatitis C virus: new targets for the design of antiviral agents.The scavenger receptor BI and its ligand, HDL: partners in crime against HCV neutralizing antibodies.The hypervariable region 1 of the E2 glycoprotein of hepatitis C virus binds to glycosaminoglycans, but this binding does not lead to infection in a pseudotype system.HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice.
P2860
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P2860
Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees
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2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@ast
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@en
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@nl
type
label
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@ast
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@en
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@nl
prefLabel
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@ast
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@en
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@nl
P2093
P2860
P356
P1476
Hepatitis C virus lacking the ...... stent infection in chimpanzees
@en
P2093
F V Chisari
R H Purcell
S Govindarajan
S U Emerson
P2860
P304
P356
10.1073/PNAS.230453597
P407
P50
P577
2000-11-21T00:00:00Z