The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling - Wikidata - awgldk - TriplyDB

The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling

The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling

http://www.wikidata.org/entity/Q27491054

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Recent progress in West Nile virus diagnosis and vaccination Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling Inhibition of protein kinase C promotes dengue virus replication Innate immunity evasion by Dengue virus The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis Virulence and Evolution of West Nile Virus, Australia, 1960-2012 Limited Effects of Type I Interferons on Kyasanur Forest Disease Virus in Cell Culture Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists Mechanism of West Nile virus neuroinvasion: a critical appraisal STAT2 signaling and dengue virus infection STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor Membrane Topology and Function of Dengue Virus NS2A Protein The many faces of the flavivirus NS5 protein in antagonism of type I interferon signaling The global ecology and epidemiology of West Nile virus Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulator The interface between methyltransferase and polymerase of NS5 is essential for flavivirus replication Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses The structure of Zika virus NS5 reveals a conserved domain conformation The IMPORTance of the Nucleus during Flavivirus Replication.Zika virus: Global health challenge, threat and current situation.Flaviviruses, an expanding threat in public health: focus on dengue, West Nile, and Japanese encephalitis virus.Tick-borne flaviviruses antagonize both IRF-1 and type I IFN signaling to inhibit dendritic cell function.A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in mice Abrogation of TLR3 inhibition by discrete amino acid changes in the C-terminal half of the West Nile virus NS1 protein.A single amino acid in nonstructural protein NS4B confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis.A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus Structural gene (prME) chimeras of St Louis encephalitis virus and West Nile virus exhibit altered in vitro cytopathic and growth phenotypes.The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon Evidence for co-evolution of West Nile Virus and house sparrows in North America.Programmed ribosomal frameshift alters expression of west nile virus genes and facilitates virus replication in birds and mosquitoes.Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling Altered protein networks and cellular pathways in severe west nile disease in mice.Treatment of yellow fever virus with an adenovirus-vectored interferon, DEF201, in a hamster model.Virulence determinants between New York 99 and Kunjin strains of West Nile virus Two distinct sets of NS2A molecules are responsible for dengue virus RNA synthesis and virion assembly Immune responses to an attenuated West Nile virus NS4B-P38G mutant strain.Comparison of the neuropathology induced by two West Nile virus strains.Genetic and phenotypic properties of vero cell-adapted Japanese encephalitis virus SA14-14-2 vaccine strain variants and a recombinant clone, which demonstrates attenuation and immunogenicity in mice.The relationship between the structure of the tick-borne encephalitis virus strains and their pathogenic properties.

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The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling

http://www.wikidata.org/entity/Q27491054

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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The NS5 Protein of the Virulen ...... on-Mediated JAK-STAT Signaling

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Aaron B Carmody

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Alan D Barrett

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Barry Rockx

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James B Wolfinbarger

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Joseph Ashour

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Kirk J Lubick

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Marshall E Bloom

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Maudry Laurent-Rolle

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Michael R Holbrook

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Peter W Mason

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular biology of flaviviruses

Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression

Blocking of the alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection

Inhibition of interferon signaling by dengue virus

NS5 of dengue virus mediates STAT2 binding and degradation

Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex

trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells.

Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of Flaviviruses

Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains.

Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist

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3503-15

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4207436

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10.1128/JVI.01161-09

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7

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84

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Alexander A. Khromykh

Adolfo García-Sastre

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2010-04-01T00:00:00Z

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41165939

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20106931

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West Nile virus

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2838099

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