A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
about
Host-Targeting Agents to Prevent and Cure Hepatitis C Virus InfectionCuring a viral infection by targeting the host: the example of cyclophilin inhibitorsNew hepatitis C virus drug discovery strategies and model systemsHigh-throughput screening and rapid inhibitor triage using an infectious chimeric Hepatitis C virusHepatitis C virus non-structural protein 3 (HCV NS3): a multifunctional antiviral targetPD 404,182 is a virocidal small molecule that disrupts hepatitis C virus and human immunodeficiency virus.Hepatitis C virus experimental model systems and antiviral drug research.Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replicationMAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles.Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes.Novel cell-based hepatitis C virus infection assay for quantitative high-throughput screening of anti-hepatitis C virus compoundsA screen for genetic suppressor elements of hepatitis C virus identifies a supercharged protein inhibitor of viral replication.Antiviral drugs against hepatitis C virus.A Dual-reporter system for real-time monitoring and high-throughput CRISPR/Cas9 library screening of the hepatitis C virus.Last stop before exit - hepatitis C assembly and release as antiviral drug targets.Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.Identification of novel anti-hepatitis C virus agents by a quantitative high throughput screen in a cell-based infection assay.The Polymerase Chain Reaction: Essential for the Development of Curative Therapy for Hepatitis CIdentification of a New Benzimidazole Derivative as an Antiviral against Hepatitis C VirusEvaluation of PD 404,182 as an anti-HIV and anti-herpes simplex virus microbicide.How hepatitis C virus invades hepatocytes: the mystery of viral entryUnderstanding the hepatitis C virus life cycle paves the way for highly effective therapies.In vitro models for analysis of the hepatitis C virus life cycle.Clinically Approved Ion Channel Inhibitors Close Gates for Hepatitis C Virus and Open Doors for Drug Repurposing in Infectious Viral Diseases.Amiodarone inhibits the entry and assembly steps of hepatitis C virus life cycle.Repurposing an old drug: A low-cost allergy medication provides new hope for hepatitis C patients.Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds.Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic heterocycles.Interplay among cellular polarization, lipoprotein metabolism and hepatitis C virus entry.
P2860
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P2860
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
description
2010 nî lūn-bûn
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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2010 թվականի փետրվարին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
A cell protection screen revea ...... e hepatitis C virus life cycle
@ast
A cell protection screen revea ...... e hepatitis C virus life cycle
@en
A cell protection screen revea ...... e hepatitis C virus life cycle
@nl
type
label
A cell protection screen revea ...... e hepatitis C virus life cycle
@ast
A cell protection screen revea ...... e hepatitis C virus life cycle
@en
A cell protection screen revea ...... e hepatitis C virus life cycle
@nl
prefLabel
A cell protection screen revea ...... e hepatitis C virus life cycle
@ast
A cell protection screen revea ...... e hepatitis C virus life cycle
@en
A cell protection screen revea ...... e hepatitis C virus life cycle
@nl
P2093
P2860
P356
P1476
A cell protection screen revea ...... e hepatitis C virus life cycle
@en
P2093
Charles M Rice
Karuppiah Chockalingam
Rudo L Simeon
Zhilei Chen
P2860
P304
P356
10.1073/PNAS.0915117107
P407
P577
2010-02-23T00:00:00Z