A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca2+ influx
about
Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activityStructure of the O-glycosylated conopeptide CcTx from Conus consors venomA conserved motif within the vitamin K-dependent carboxylase gene is widely distributed across animal phylaDiversity of conotoxin gene superfamilies in the venomous snail, Conus victoriaeIsolation and characterization of a novel conus peptide with apparent antinociceptive activity.lambda-conotoxins, a new family of conotoxins with unique disulfide pattern and protein folding. Isolation and characterization from the venom of Conus marmoreus.Sequence requirements for the N-methyl-D-aspartate receptor antagonist activity of conantokin-R.Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is alpha-D-Gal-(1-->3)-alpha-D-GalNAc.Two toxins from Conus striatus that individually induce tetanic paralysis.A 'conovenomic' analysis of the milked venom from the mollusk-hunting cone snail Conus textile--the pharmacological importance of post-translational modifications.The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea.Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history.gamma -Glutamyl carboxylation: An extracellular posttranslational modification that antedates the divergence of molluscs, arthropods, and chordates.Characterization of conantokin Rl-A: molecular phylogeny as structure/function study.The first gamma-carboxyglutamic acid-containing contryphan. A selective L-type calcium ion channel blocker isolated from the venom of Conus marmoreus.Conotoxin gene superfamilies.Native pyroglutamation of huwentoxin-IV: a post-translational modification that increases the trapping ability to the sodium channel.A novel conotoxin, qc16a, with a unique cysteine framework and foldingDe novo sequencing and disulfide mapping of a bromotryptophan-containing conotoxin by Fourier transform ion cyclotron resonance mass spectrometry.Various conotoxin diversifications revealed by a venomic study of Conus flavidusTargeting voltage-gated calcium channels: developments in peptide and small-molecule inhibitors for the treatment of neuropathic pain.Glycosylation of conotoxins.Incorporation of post-translational modified amino acids as an approach to increase both chemical and biological diversity of conotoxins and conopeptides.A Transcriptomic Survey of Ion Channel-Based Conotoxins in the Chinese Tubular Cone Snail (Conus betulinus).Identification and molecular diversity of T-superfamily conotoxins from Conus lividus and Conus litteratus.Expression and characterization of recombinant vitamin K-dependent gamma-glutamyl carboxylase from an invertebrate, Conus textile.Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (CaV) Channels.Using optimized collision energies and high resolution, high accuracy fragment ion selection to improve glycopeptide detection by precursor ion scanning.In HspA from Helicobacter pylori vicinal disulfide bridges are a key determinant of domain B structure.Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery.Sequencing of T-superfamily conotoxins from Conus virgo: pyroglutamic acid identification and disulfide arrangement by MALDI mass spectrometry.Classes, Databases, and Prediction Methods of Pharmaceutically and Commercially Important Cystine-Stabilized Peptides.
P2860
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P2860
A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca2+ influx
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@ast
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@en
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@nl
type
label
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@ast
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@en
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@nl
prefLabel
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@ast
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@en
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@nl
P2093
P2860
P356
P1476
A conotoxin from Conus textile ...... educes presynaptic Ca2+ influx
@en
P2093
D E Kalume
E Czerwiec
E Lucas-Meunier
I Dahlqvist
J D Baleja
P2860
P304
P356
10.1073/PNAS.96.10.5758
P407
P577
1999-05-11T00:00:00Z