Protein plasticity to the extreme: changing the topology of a 4-alpha-helical bundle with a single amino acid substitution
about
Structuprint: a scalable and extensible tool for two-dimensional representation of protein surfaces.Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalphaCysteine-free rop: A four-helix bundle core mutant has wild-type stability and structure but dramatically different unfolding kineticsStructural plasticity of 4- -helical bundles exemplified by the puzzle-like molecular assembly of the Rop proteinDe novo design of helical bundles as models for understanding protein folding and function.FeatureMap3D--a tool to map protein features and sequence conservation onto homologous structures in the PDBGSAFold: a new application of GSA to protein structure prediction.Combinatorial approaches to protein stability and structure.Symmetry and frustration in protein energy landscapes: a near degeneracy resolves the Rop dimer-folding mystery.Assisted peptide folding by surface pattern recognition.Structural plasticity of an aminoacyl-tRNA synthetase active siteMore than the sum of their parts: on the evolution of proteins from peptides.Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitutionEsxB, a secreted protein from Bacillus anthracis forms two distinct helical bundles.Mutations as trapdoors to two competing native conformations of the Rop-dimerThe crystal structure of the calcium-bound con-G[Q6A] peptide reveals a novel metal-dependent helical trimerGenetic variation in CYP3A43 is associated with response to antipsychotic medication.Purification, crystallization and preliminary X-ray diffraction analysis of a variant of the ColE1 Rop protein.PeptiSite: a structural database of peptide binding sites in 4D.Generating artificial homologous proteins according to the representative family character in molecular mechanics properties--an attempt in validating an underlying rule of protein evolution.
P2860
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P2860
Protein plasticity to the extreme: changing the topology of a 4-alpha-helical bundle with a single amino acid substitution
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Protein plasticity to the extr ...... single amino acid substitution
@ast
Protein plasticity to the extr ...... single amino acid substitution
@en
Protein plasticity to the extr ...... single amino acid substitution
@nl
type
label
Protein plasticity to the extr ...... single amino acid substitution
@ast
Protein plasticity to the extr ...... single amino acid substitution
@en
Protein plasticity to the extr ...... single amino acid substitution
@nl
prefLabel
Protein plasticity to the extr ...... single amino acid substitution
@ast
Protein plasticity to the extr ...... single amino acid substitution
@en
Protein plasticity to the extr ...... single amino acid substitution
@nl
P2093
P1433
P1476
Protein plasticity to the extr ...... single amino acid substitution
@en
P2093
G Cesareni
M Kokkinidis
N M Glykos
P304
P356
10.1016/S0969-2126(99)80081-1
P577
1999-06-15T00:00:00Z