The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis
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A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM databaseThree-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricusStructure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysisStructural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylaseGlycal Formation in Crystals of Uridine Phosphorylase ,Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidaseA Study on the Interaction of Rhodamine B with Methylthioadenosine Phosphorylase Protein Sourced from an Antarctic Soil Metagenomic LibraryA corrected space group for Sulfolobus sulfataricus 5'-deoxy-5'-methylthioadenosine phosphorylase IIStructural analyses reveal two distinct families of nucleoside phosphorylasesCrystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage PathwayBiochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.Enhancing MAD F(A) data for substructure determination.Continuous Fluorescence Assays for Reactions Involving AdenineHeat Capacity Changes for Transition-State Analogue Binding and Catalysis with Human 5'-Methylthioadenosine Phosphorylase.Identification and characterization of two adenosine phosphorylase activities in Mycobacterium smegmatis.Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimicsAssociation of common variants in MTAP with susceptibility and overall survival of osteosarcoma: a two-stage population-based study in Han Chinese.Breaking the singleton of germination proteaseStructural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.Molecular dynamics study of the effect of active site protonation on Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase.Primate genome gain and loss: a bone dysplasia, muscular dystrophy, and bone cancer syndrome resulting from mutated retroviral-derived MTAP transcripts.Transition-state structure of human 5'-methylthioadenosine phosphorylase.Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding.Molecular characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase-deficient mutant clones of murine lymphoma cell line R1.1.Efficient Fludarabine-Activating PNP From Archaea as a Guidance for Redesign the Active Site of E. Coli PNP.Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.Leishmania infantum 5'-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target.4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents
P2860
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P2860
The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The structure of human 5'-deox ...... ubstrate binding and catalysis
@ast
The structure of human 5'-deox ...... ubstrate binding and catalysis
@en
The structure of human 5'-deox ...... ubstrate binding and catalysis
@nl
type
label
The structure of human 5'-deox ...... ubstrate binding and catalysis
@ast
The structure of human 5'-deox ...... ubstrate binding and catalysis
@en
The structure of human 5'-deox ...... ubstrate binding and catalysis
@nl
prefLabel
The structure of human 5'-deox ...... ubstrate binding and catalysis
@ast
The structure of human 5'-deox ...... ubstrate binding and catalysis
@en
The structure of human 5'-deox ...... ubstrate binding and catalysis
@nl
P2093
P1433
P1476
The structure of human 5'-deox ...... ubstrate binding and catalysis
@en
P2093
S E Ealick
T C Appleby
P304
P356
10.1016/S0969-2126(99)80084-7
P407
P577
1999-06-15T00:00:00Z