Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
about
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor bindingPrinciples of antibody-mediated TNF receptor activationCrystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificityCrystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificityCrystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolutionLigand-receptor binding revealed by the TNF family member TALL-1Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5Solution structure of the cysteine-rich domain in Fn14, a member of the tumor necrosis factor receptor superfamilyBiochemical and Structural Characterization of the Human TL1A Ectodomain ,Structure-based development of a receptor activator of nuclear factor- B ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosisCrystallographic and Mutational Analysis of the CD40-CD154 Complex and Its Implications for Receptor ActivationDecoy Strategies: The Structure of TL1A:DcR3 ComplexRANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy ReceptorStructure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactionsDimerization of LT R by LT 1 2 is necessary and sufficient for signal transductionRole of nanotechnology and gene delivery systems in TRAIL-based therapiesMolecular characterization of CD40 signaling intermediatesFollowing a TRAIL: update on a ligand and its five receptorsIdentification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)Overview of protein structural and functional folds.The methionine-aromatic motif plays a unique role in stabilizing protein structure.The role of tumor necrosis factor receptor superfamily members in mammalian brain development, function and homeostasisThe structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex.High-throughput screening of cell death inducible short peptides from TNF-related apoptosis-inducing ligand sequence.Synthetic constrained peptide selectively binds and antagonizes death receptor 5.Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cellsTargeting a novel N-terminal epitope of death receptor 5 triggers tumor cell death.TNF alpha and the TNF receptor superfamily: structure-function relationship(s).The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase.Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosisThe pre-ligand binding assembly domain: a potential target of inhibition of tumour necrosis factor receptor function.TRAIL and interferon-alpha act synergistically to induce renal cell carcinoma apoptosis.Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex.Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants.A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone lossDesigned tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor.Molecular identification of an MHC-independent ligand recognized by a human {alpha}/{beta} T-cell receptor.Accelerated degradation of FADD and procaspase 8 in cells expressing human papilloma virus 16 E6 impairs TRAIL-mediated apoptosis.Gene expression profiling associated with angiotensin II type 2 receptor-induced apoptosis in human prostate cancer cellsThe TRAIL to viral pathogenesis: the good, the bad and the ugly
P2860
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P2860
Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@ast
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@en
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@nl
type
label
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@ast
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@en
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@nl
prefLabel
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@ast
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@en
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@nl
P2093
P3181
P356
P1476
Structure of the TRAIL-DR5 com ...... ficity in apoptotic initiation
@en
P2093
D I Stuart
G R Screaton
J M Grimes
J Mongkolsapaya
P2888
P304
P3181
P356
10.1038/14935
P407
P577
1999-11-01T00:00:00Z
P6179
1050219804