Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change
about
Prion protein-specific antibodies that detect multiple TSE agents with high sensitivityCrystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomersChanging a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers.Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form.Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversionMapping the early steps in the pH-induced conformational conversion of the prion protein.Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation.PrP conformational transitions alter species preference of a PrP-specific antibody.Disulfide mapping reveals the domain swapping as the crucial process of the structural conversion of prion proteinThe Effects of Ca2+ Concentration and E200K Mutation on the Aggregation Propensity of PrPC: A Computational Study.Characterization of conformation-dependent prion protein epitopes.Electron crystallography of the scrapie prion protein complexed with heavy metals.Conformational selection in amyloid-based immunotherapy: Survey of crystal structures of antibody-amyloid complexes.Antibody-Mediated Catalysis in Infection and Immunity.Vitamin D 2 interacts with Human PrP(c) (90-231) and breaks PrP(c) oligomerization in vitro.Fate of pathological prion (PrP(sc)92-138) in soil and water: prion-clay nanoparticle molecular dynamics.Helix-coil transition of PrP106-126: molecular dynamic study.Acidic pH and detergents enhance in vitro conversion of human brain PrPC to a PrPSc-like form.Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein.Immunoglobulins in urine of hamsters with scrapie.Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains.
P2860
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P2860
Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Antibody binding defines a str ...... -->PrPSc conformational change
@ast
Antibody binding defines a str ...... -->PrPSc conformational change
@en
Antibody binding defines a str ...... -->PrPSc conformational change
@nl
type
label
Antibody binding defines a str ...... -->PrPSc conformational change
@ast
Antibody binding defines a str ...... -->PrPSc conformational change
@en
Antibody binding defines a str ...... -->PrPSc conformational change
@nl
prefLabel
Antibody binding defines a str ...... -->PrPSc conformational change
@ast
Antibody binding defines a str ...... -->PrPSc conformational change
@en
Antibody binding defines a str ...... -->PrPSc conformational change
@nl
P2093
P356
P1476
Antibody binding defines a str ...... gt;PrPSc conformational change
@en
P2093
D R Burton
R A Williamson
R J Fletterick
P304
P356
10.1006/JMBI.1999.3193
P407
P577
1999-11-05T00:00:00Z