An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism
about
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.G17V RHOA: Genetic evidence of GTP-unbound RHOA playing a role in tumorigenesis in T cellsStructure of the Dominant Negative S17N Mutant of Ras ,Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutSStructure of Shigella IpgB2 in Complex with Human RhoA: IMPLICATIONS FOR THE MECHANISM OF BACTERIAL GUANINE NUCLEOTIDE EXCHANGE FACTOR MIMICRYCrystal structure of mouse RhoA:GTPγS complex in a centered latticeStructural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factorPhosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranesLipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA.Generation of a single chain antibody variable fragment (scFv) to sense selectively RhoB activation.Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled gamma-phosphate-linked GTP analogs.Antiviral activity of RhoA-derived peptides against respiratory syncytial virus is dependent on formation of peptide dimersImplications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression.RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones.Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle.Somatic RHOA mutation in angioimmunoblastic T cell lymphoma.Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange.Functional analysis of cdc42 residues required for Guanine nucleotide exchange.Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II.Structural and mechanistic insights into the interaction between Rho and mammalian Dia.Molecular mechanism of constitutively active Rab11A was revealed by crystal structure of Rab11A S20V.
P2860
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P2860
An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
An open conformation of switch ...... the GDP/GTP exchange mechanism
@ast
An open conformation of switch ...... the GDP/GTP exchange mechanism
@en
An open conformation of switch ...... the GDP/GTP exchange mechanism
@nl
type
label
An open conformation of switch ...... the GDP/GTP exchange mechanism
@ast
An open conformation of switch ...... the GDP/GTP exchange mechanism
@en
An open conformation of switch ...... the GDP/GTP exchange mechanism
@nl
prefLabel
An open conformation of switch ...... the GDP/GTP exchange mechanism
@ast
An open conformation of switch ...... the GDP/GTP exchange mechanism
@en
An open conformation of switch ...... the GDP/GTP exchange mechanism
@nl
P2093
P2860
P356
P1476
An open conformation of switch ...... the GDP/GTP exchange mechanism
@en
P2093
P2860
P304
P356
10.1074/JBC.M910274199
P407
P577
2000-06-16T00:00:00Z