The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase
about
Potential use of sugar binding proteins in reactors for regeneration of CO2 fixation acceptor D-Ribulose-1,5-bisphosphatePPD v1.0--an integrated, web-accessible database of experimentally determined protein pKa valuesStructural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle DynamicsModeling, mutagenesis, and structural studies on the fully conserved phosphate-binding loop (loop 8) of triosephosphate isomerase: toward a new substrate specificityStructural determinants for ligand binding and catalysis of triosephosphate isomeraseCrystal structure of triosephosphate isomerase complexed with 2-phosphoglycolate at 0.83-A resolutionThe pKa Values of Acidic and Basic Residues Buried at the Same Internal Location in a Protein Are Governed by Different FactorsProbing the role of highly conserved residues in triosephosphate isomerase--analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzymeReversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteinsStructural and thermodynamic folding characterization of triosephosphate isomerases from Trichomonas vaginalis reveals the role of destabilizing mutations following gene duplication.Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.On the evaluation and optimization of protein X-ray structures for pKa calculations.The role of protonation states in ligand-receptor recognition and binding.A guide to the effects of a large portion of the residues of triosephosphate isomerase on catalysis, stability, druggability, and human disease.Thermodynamic characterization of yeast triosephosphate isomerase refolding: insights into the interplay between function and stability as reasons for the oligomeric nature of the enzyme.pKD: re-designing protein pKa values.Redesigning protein pKa values.Highly perturbed pKa values in the unfolded state of hen egg white lysozyme.Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities.
P2860
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P2860
The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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name
The ionization of a buried glu ...... ana triose phosphate isomerase
@ast
The ionization of a buried glu ...... ana triose phosphate isomerase
@en
The ionization of a buried glu ...... ana triose phosphate isomerase
@nl
type
label
The ionization of a buried glu ...... ana triose phosphate isomerase
@ast
The ionization of a buried glu ...... ana triose phosphate isomerase
@en
The ionization of a buried glu ...... ana triose phosphate isomerase
@nl
prefLabel
The ionization of a buried glu ...... ana triose phosphate isomerase
@ast
The ionization of a buried glu ...... ana triose phosphate isomerase
@en
The ionization of a buried glu ...... ana triose phosphate isomerase
@nl
P2093
P2860
P3181
P1433
P1476
The ionization of a buried glu ...... ana triose phosphate isomerase
@en
P2093
A M Lambeir
B V Norledge
J Backmann
J E Nielsen
J Ruiz-Sanz
R K Wierenga
V Filimonov
P2860
P304
P3181
P356
10.1046/J.1432-1327.2000.01254.X
P407
P577
2000-05-01T00:00:00Z