A new allosteric site in glycogen phosphorylase b as a target for drug interactions
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Glycogen synthesis correlates with androgen-dependent growth arrest in prostate cancer.The role of triterpenes in the management of diabetes mellitus and its complicationsTargeting glycogen metabolism in bladder cancerFlavopiridol inhibits glycogen phosphorylase by binding at the inhibitor siteNatural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase bGlycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapyFatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytesGlycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus.Structure-based predictive models for allosteric hot spots.Reaction kinetics of substrate transglycosylation catalyzed by TreX of Sulfolobus solfataricus and effects on glycogen breakdownA novel and efficient tool for locating and characterizing protein cavities and binding sites.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Current therapies and emerging drugs in the pipeline for type 2 diabetes.Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharidesResidues crucial for maintaining short paths in network communication mediate signaling in proteinsStructural and spectral investigations of the recently synthesized chalcone (E)-3-mesityl-1-(naphthalen-2-yl) prop-2-en-1-one, a potential chemotherapeutic agent.Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages.Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.Bioassay-Guided Isolation of Sesquiterpene Coumarins from Ferula narthex Bioss: A New Anticancer Agent.Glycogen phosphorylase inhibitors: a patent review (2008 - 2012).McArdle Disease: Update of Reported Mutations and Polymorphisms in the PYGM Gene.New Diethyl Ammonium Salt of Thiobarbituric Acid Derivative: Synthesis, Molecular Structure Investigations and Docking Studies.Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment.Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is markedly dependent on the activation state of the enzyme.The effect of glucose on the potency of two distinct glycogen phosphorylase inhibitors.Inhibition of autophagic proteolysis by inhibitors of phosphoinositide 3-kinase can interfere with the regulation of glycogen synthesis in isolated hepatocytes.Integrated effects of multiple modulators on human liver glycogen phosphorylase a.
P2860
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P2860
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@ast
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@en
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@nl
type
label
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@ast
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@en
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@nl
prefLabel
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@ast
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@en
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@nl
P2093
P1433
P1476
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
@en
P2093
K E Tsitsanou
L N Johnson
N G Gavalas
N G Oikonomakos
V T Skamnaki
P304
P356
10.1016/S0969-2126(00)00144-1
P577
2000-06-15T00:00:00Z