The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2
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Eukaryotic translation-initiation factor eIF2beta binds to protein kinase CK2: effects on CK2alpha activityProtein kinase CK2 and protein kinase D are associated with the COP9 signalosomeStructural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazoleInhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insightBiochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibitionStructure of human protein kinase CK2α2 with a potent indazole-derivative inhibitorQuinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2″-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside KinasesA novel role of Sp1 and Sp3 in the interferon-gamma -mediated suppression of macrophage lipoprotein lipase gene transcription.Inhibition of protein kinase CK2 prevents the progression of glomerulonephritisProtein kinases CK1 and CK2 as new targets for neurodegenerative diseases.Inhibiting NF-κB activation by small molecules as a therapeutic strategy.Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)Anti-cytomegalovirus activity of the anthraquinone atanyl blue PRL.Actin dynamics is controlled by a casein kinase II and phosphatase 2C interplay on Toxoplasma gondii Toxofilin.Casein Kinase 2 (CK2)-mediated Phosphorylation of Hsp90β as a Novel Mechanism of Rifampin-induced MDR1 ExpressionEmodin is a novel alkaline nuclease inhibitor that suppresses herpes simplex virus type 1 yields in cell cultures.Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor.Structural and functional determinants of protein kinase CK2α: facts and open questions.Antiviral effect of emodin from Rheum palmatum against coxsakievirus B5 and human respiratory syncytial virus in vitro.In vitro and in vivo studies of the inhibitory effects of emodin isolated from Polygonum cuspidatum on Coxsakievirus B₄.An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.Casein kinase 2 inhibition attenuates androgen receptor function and cell proliferation in prostate cancer cells.Structure-Based Pharmacophore Modeling from Multicomplex: a Comprehensive Pharmacophore Generation of Protein Kinase CK2 and Virtual Screening Based on it for Novel Inhibitors.4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin.Kinase selectivity potential for inhibitors targeting the ATP binding site: a network analysis.Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis.Emodin modulates epigenetic modifications and suppresses bladder carcinoma cell growth.A novel allosteric site in casein kinase 2α discovered using combining bioinformatics and biochemistry methods.A π-Halogen Bond of Dibenzofuranones with the Gatekeeper Phe113 in Human Protein Kinase CK2 Leads to Potent Tight Binding Inhibitors.FIKK Kinase, a Ser/Thr Kinase Important to Malaria Parasites, Is Inhibited by Tyrosine Kinase Inhibitors.
P2860
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P2860
The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
The replacement of ATP by the ...... tic site of protein kinase CK2
@ast
The replacement of ATP by the ...... tic site of protein kinase CK2
@en
The replacement of ATP by the ...... tic site of protein kinase CK2
@nl
type
label
The replacement of ATP by the ...... tic site of protein kinase CK2
@ast
The replacement of ATP by the ...... tic site of protein kinase CK2
@en
The replacement of ATP by the ...... tic site of protein kinase CK2
@nl
prefLabel
The replacement of ATP by the ...... tic site of protein kinase CK2
@ast
The replacement of ATP by the ...... tic site of protein kinase CK2
@en
The replacement of ATP by the ...... tic site of protein kinase CK2
@nl
P2093
P356
P1476
The replacement of ATP by the ...... tic site of protein kinase CK2
@en
P2093
Battistutta R
De Moliner E
Papinutto E
P304
29618-29622
P356
10.1074/JBC.M004257200
P407
P577
2000-09-01T00:00:00Z