Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine
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Prodrugs for Gene-Directed Enzyme-Prodrug Therapy (Suicide Gene Therapy)The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinaseCrystal structure of varicella zoster virus thymidine kinaseFunctional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase. Investigations of the putative catalytic glutamate-arginine pair and of residues responsible for substrate specificityBiochemical and structural characterization of (South)-methanocarbathymidine that specifically inhibits growth of herpes simplex virus type 1 thymidine kinase-transduced osteosarcoma cellsPharmacophore-based virtual screening versus docking-based virtual screening: a benchmark comparison against eight targets.Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections.N-Methanocarbathymidine is more effective than acyclovir for treating neonatal herpes simplex virus infection in guinea pigsAntiviral Activity of 4'-thioIDU and Thymidine Analogs against OrthopoxvirusesSelective Phosphorylation of South and North-Cytidine and Adenosine Methanocarba-Nucleosides by Human Nucleoside and Nucleotide Kinases Correlates with Their Growth Inhibitory Effects on Cultured Cells.The rational of catalytic activity of herpes simplex virus thymidine kinase. a combined biochemical and quantum chemical study.Methodology and problems of protein-ligand docking: case study of dihydroorotate dehydrogenase, thymidine kinase, and phosphodiesterase 4.
P2860
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P2860
Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@ast
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@en
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@nl
type
label
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@ast
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@en
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@nl
prefLabel
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@ast
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@en
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@nl
P2093
P356
P1433
P1476
Kinetics and crystal structure ...... (North)-methanocarba-thymidine
@en
P2093
G E Schulz
L Scapozza
V E Marquez
P304
P356
10.1021/BI000668Q
P407
P50
P577
2000-08-01T00:00:00Z