Crystal structure of recombinant native SDF-1alpha with additional mutagenesis studies: an attempt at a more comprehensive interpretation of accumulated structure-activity relationship data
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Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1 ) Binding to HeparinMonomeric structure of the cardioprotective chemokine SDF-1/CXCL12Structural Basis of CXCR4 Sulfotyrosine Recognition by the Chemokine SDF-1/CXCL12Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine familyStructural insight into the evolution of a new chemokine family from zebrafishStructural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokineElucidating a key component of cancer metastasis: CXCL12 (SDF-1α) binding to CXCR4.Secreted CXCL12 (SDF-1) forms dimers under physiological conditions.On-column refolding of recombinant chemokines for NMR studies and biological assays.The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4.Small neutralizing molecules to inhibit actions of the chemokine CXCL12.Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells.A novel CXCR4-selective high-affinity fluorescent probe and its application in competitive binding assaysStructural Analysis of Chemokine Receptor-Ligand Interactions.Dual targeting of the chemokine receptors CXCR4 and ACKR3 with novel engineered chemokines.Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR4.Characterization of the stromal cell-derived factor-1alpha-heparin complex.Exploiting agonist biased signaling of chemokines to target cancer.Heparan sulfate differentially controls CXCL12α- and CXCL12γ-mediated cell migration through differential presentation to their receptor CXCR4.Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12)Backbone dynamics of SDF-1alpha determined by NMR: interpretation in the presence of monomer-dimer equilibriumStructural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin.Structural basis of the interactions between CXCR4 and CXCL12/SDF-1 revealed by theoretical approaches.
P2860
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P2860
Crystal structure of recombinant native SDF-1alpha with additional mutagenesis studies: an attempt at a more comprehensive interpretation of accumulated structure-activity relationship data
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Crystal structure of recombina ...... ure-activity relationship data
@ast
Crystal structure of recombina ...... ure-activity relationship data
@en
Crystal structure of recombina ...... ure-activity relationship data
@nl
type
label
Crystal structure of recombina ...... ure-activity relationship data
@ast
Crystal structure of recombina ...... ure-activity relationship data
@en
Crystal structure of recombina ...... ure-activity relationship data
@nl
prefLabel
Crystal structure of recombina ...... ure-activity relationship data
@ast
Crystal structure of recombina ...... ure-activity relationship data
@en
Crystal structure of recombina ...... ure-activity relationship data
@nl
P2093
P1476
Crystal structure of recombina ...... ure-activity relationship data
@en
P2093
P304
P356
10.1089/10799900050116390
P577
2000-08-01T00:00:00Z