The crystal structure of the fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone bip
about
The structure of a folding intermediate provides insight into differences in immunoglobulin amyloidogenicityHierarchical formation of disulfide bonds in the immunoglobulin Fc fragment is assisted by protein-disulfide isomerase.Localization of BiP to translating ribosomes increases soluble accumulation of secreted eukaryotic proteins in an Escherichia coli cell-free systemA phaseolin domain involved directly in trimer assembly is a determinant for binding by the chaperone BiP.Alteration of amino acid residues at the L-chain N-terminus and in complementarity-determining region 3 increases affinity of a recombinant F(ab) for the human N blood group antigen.MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors.An unfolded CH1 domain controls the assembly and secretion of IgG antibodies.A residue-specific shift in stability and amyloidogenicity of antibody variable domains.Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains.Synthesis and characterization of a functional intact IgG in a prokaryotic cell-free expression system.
P2860
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P2860
The crystal structure of the fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone bip
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The crystal structure of the f ...... raction with the chaperone bip
@ast
The crystal structure of the f ...... raction with the chaperone bip
@en
The crystal structure of the f ...... raction with the chaperone bip
@nl
type
label
The crystal structure of the f ...... raction with the chaperone bip
@ast
The crystal structure of the f ...... raction with the chaperone bip
@en
The crystal structure of the f ...... raction with the chaperone bip
@nl
prefLabel
The crystal structure of the f ...... raction with the chaperone bip
@ast
The crystal structure of the f ...... raction with the chaperone bip
@en
The crystal structure of the f ...... raction with the chaperone bip
@nl
P2093
P2860
P921
P356
P1476
The crystal structure of the f ...... raction with the chaperone bip
@en
P2093
A de La Calle
C A Frederick
J G Augustine
P2860
P304
P356
10.1074/JBC.M005221200
P407
P577
2001-02-02T00:00:00Z