Structure and dynamics of micelle-bound neuropeptide Y: comparison with unligated NPY and implications for receptor selection
about
Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug actionThe NMR-derived conformation of neuropeptide F from Moniezia expansaNMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles. Conformational changes are a key to antimicrobial activityBiophysical methods to study ligand-receptor interactions of neuropeptide YMembrane-inserted conformation of transmembrane domain 4 of divalent-metal transporter.NMR conformational studies of micelle-bound orexin-B: a neuropeptide involved in the sleep/awake cycle and feeding regulation.NMRDyn: a program for NMR relaxation studies of protein association.Non-specific binding and general cross-reactivity of Y receptor agonists are correlated and should importantly depend on their acidic sectors.Micellar nanomedicine of human neuropeptide Y.NMR studies in dodecylphosphocholine of a fragment containing the seventh transmembrane helix of a G-protein-coupled receptor from Saccharomyces cerevisiae.Are hormones from the neuropeptide Y family recognized by their receptors from the membrane-bound state?Recognition of neurohormones of the NPY family by their receptors.Interaction of the neurotransmitter, neuropeptide Y, with phospholipid membranes: film balance and fluorescence microscopy studies.NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins.Interaction of the neurotransmitter, neuropeptide Y, with phospholipid membranes: infrared spectroscopic characterization at the air/water interface.Membrane catalysis of peptide-receptor binding.Anticonvulsant neuropeptides as drug leads for neurological diseases.The neuropeptide Y monomer in solution is not folded in the pancreatic-polypeptide fold.NPY binds with heme to form a NPY-heme complex: enhancing peroxidase activity in free heme and promoting NPY nitration and inactivation.Cell membranes… and how long drugs may exert beneficial pharmacological activity in vivoMolecular mechanisms for the persistent bronchodilatory effect of the beta 2-adrenoceptor agonist salmeterolMembrane surface-associated helices promote lipid interactions and cellular uptake of human calcitonin-derived cell penetrating peptides.Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y₂ Receptor Binding and Activation.Role of proline, cysteine and a disulphide bridge in the structure and activity of the anti-microbial peptide gaegurin 5.Structure and topology of the transmembrane domain 4 of the divalent metal transporter in membrane-mimetic environments.Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. II: nuclear magnetic resonance experimentsElectron paramagnetic resonance backbone dynamics studies on spin-labelled neuropeptide Y analogues.Semisynthesis and characterization of the first analogues of pro-neuropeptide y.The NMR-derived conformation of orexin-A: an orphan G-protein coupled receptor agonist involved in appetite regulation and sleep.Characterization the effects of structure and energetics of intermolecular interactions on the oligomerization of peptides in aqueous 2, 2, 2-trifluoroethanol via circular dichroism and nuclear magnetic resonance spectroscopy.Elucidation by NMR solution of neurotensin in small unilamellar vesicle environment: molecular surveys for neurotensin receptor recognition.Neuropeptide Y reduces the expression of PLCB2, PLCD1 and selected PLC genes in cultured human endothelial cells.Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands.Mutational Analysis of Neuropeptide Y Reveals Unusual Thermal Stability Linked to Higher-Order Self-Association.Understanding GPCR Recognition and Folding from NMR Studies of Fragments.Link between a high for drug binding and a fast clinical action: to be or not to be?A Chimeric GPCR Model Mimicking the Ligand Binding Site of the Human Y1 Receptor Studied by NMR Spectroscopy
P2860
Q24595639-8508F811-A5CC-45F7-B713-3A14F376E2D1Q27639028-C729D35B-C9AC-402F-BE2A-D0F17221FAB4Q27640413-FC2C110B-7D73-4203-871E-F8B2A445F8F7Q28220437-B77EFA7E-4B76-4E7D-B371-B524DDC9953DQ30778451-028C9762-9C77-41FA-BFBA-5BAD835E3877Q33194998-23AE150E-1ED4-4560-B9D4-8D0558DEC2F3Q33388229-0561DD2D-CD3C-48E8-A2BB-0A337238BAA4Q34511139-11A07B69-5DD3-481A-89DA-BEEC16C031ABQ35000999-B4302B10-95C5-474A-8356-2E3539AD0606Q35850937-FCC06DC3-A249-48A5-8D5F-02B07CCBE2FFQ36204247-4732CBDC-052F-4E2E-86D6-2BA585B40C7DQ36659833-991C6BA0-9974-4D0B-8EC6-76946DFF620BQ36909513-DF88C8EA-B549-4D02-B0C8-41BA5D7E9BE2Q37052031-C7E08F27-8003-4B98-BCDA-BF4ED70016ACQ37060499-08DCD9B2-6971-4433-A5CA-3894F069CC3BQ37746973-6BE93A97-5910-4A29-8304-87CF1AD48389Q37845684-9D43F874-3EC6-4F33-A99C-F37C5D179733Q38270044-6A55B47C-B6EB-4D9F-B016-C7F2246B4574Q38665001-5984E3ED-CB18-4A7D-BF7B-BD24E321C8D9Q38822818-33A5EF0A-21FD-42DB-8EE0-E1A7C67668D2Q39826205-FAACF4E4-BBFA-4AC9-827B-80A69723AEBCQ40369050-6203234E-5391-4989-8316-293EB6E64EE4Q40964685-146CCBD7-3FBB-4B18-AF06-E426646519ACQ42157431-1EB27613-0279-4923-8A5C-87468E52F825Q42626564-DA22D212-1387-44F6-AC65-D372BDF633D2Q42756238-D8E75849-B416-4ED9-9C73-2D37DDD167E1Q44275356-934F298D-80AC-49BA-AE60-8AB6F794A17AQ44436759-361F2384-1033-4C39-86CE-971C25944B2AQ44574021-9BA250C1-D914-4B73-9DAB-774A3E38CDF2Q46555245-DF29C8C4-7036-4B1B-A05A-14A8DF18E946Q48396442-7AC0FA82-43C0-45C8-AA25-8BE5CA89A2D3Q48733055-B86D00C4-7D8E-4591-B0F2-457EA8BFE052Q51800848-8CD1B3B1-998D-4EEC-A30B-A3670C4ABE8FQ52331474-E2CCCE5A-7E84-4515-9AC9-AC2DF67C4CACQ54203381-BBD0318C-6F6D-4096-A268-1501A67F14A9Q57133316-3B5F6A9B-1BBE-43FE-867E-6972F7D1E6B9Q57794644-C037031C-79E2-49BE-BBCE-938D3FC6BE95
P2860
Structure and dynamics of micelle-bound neuropeptide Y: comparison with unligated NPY and implications for receptor selection
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structure and dynamics of mice ...... cations for receptor selection
@ast
Structure and dynamics of mice ...... cations for receptor selection
@en
Structure and dynamics of mice ...... cations for receptor selection
@nl
type
label
Structure and dynamics of mice ...... cations for receptor selection
@ast
Structure and dynamics of mice ...... cations for receptor selection
@en
Structure and dynamics of mice ...... cations for receptor selection
@nl
prefLabel
Structure and dynamics of mice ...... cations for receptor selection
@ast
Structure and dynamics of mice ...... cations for receptor selection
@en
Structure and dynamics of mice ...... cations for receptor selection
@nl
P2093
P356
P1476
Structure and dynamics of mice ...... cations for receptor selection
@en
P2093
A G Beck-Sickinger
P304
P356
10.1006/JMBI.2000.4264
P407
P577
2001-01-12T00:00:00Z