Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase - Wikidata - awgldk - TriplyDB

Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase

Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase

http://www.wikidata.org/entity/Q27629024

about

Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease Detachment of Actinobacillus actinomycetemcomitans biofilm cells by an endogenous beta-hexosaminidase activity Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 beta-N-acetylhexosaminidase inhibitor X-ray structure of human acid-β-glucosidase, the defective enzyme in Gaucher disease Crystal structures of Geobacillus stearothermophilus alpha-glucuronidase complexed with its substrate and products: mechanistic implications Structural insights into the processivity of endopolygalacturonase I from Aspergillus niger Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance Insight into a strategy for attenuating AmpC-mediated β-lactam resistance: Structural basis for selective inhibition of the glycoside hydrolase NagZ Structural Determinants of an Insect -N-Acetyl-D-hexosaminidase Specialized as a Chitinolytic Enzyme Active-pocket size differentiating insectile from bacterial chitinolytic β-N-acetyl-D-hexosaminidases Structural Basis for the Substrate Specificity of a Novel -N-Acetylhexosaminidase StrH Protein from Streptococcus pneumoniae R6 Structural Insights into Cellulolytic and Chitinolytic Enzymes Revealing Crucial Residues of Insect β-N-acetyl-D-hexosaminidase Crystal Structures of a Glycoside Hydrolase Family 20 Lacto-N-biosidase from Bifidobacterium bifidum Gaining insight into the inhibition of glycoside hydrolase family 20 exo-β-N-acetylhexosaminidases using a structural approach Crystal Structure of Streptococcus pyogenes Csn2 Reveals Calcium-Dependent Conformational Changes in Its Tertiary and Quaternary Structure Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: INTRACELLULAR -O-LINKED N-GLYCOLYLGLUCOSAMINE (GlcNGc), UDP-GlcNGc, AND THE BIOCHEMICAL AND STRUCTURAL RATIONALE FOR THE SUBSTRATE TOLERANCE OF -O-LINKED -N-ACETYLGLUCOSAMINIDASE Inhibition of the family 20 glycoside hydrolase catalytic modules in the Streptococcus pneumoniae exo-β-D-N-acetylglucosaminidase, StrH Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to β-lactams Structural and biochemical characterization of the β-N-acetylglucosaminidase from Thermotoga maritima: toward rationalization of mechanistic knowledge in the GH73 family Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity Structural-Functional Analysis Reveals a Specific Domain Organization in Family GH20 Hexosaminidases Structural and Biochemical Insights into the Peptidoglycan Hydrolase Domain of FlgJ from Salmonella typhimurium Probing the Catalytic Mechanism of Vibrio harveyi GH20 β-N-Acetylglucosaminidase by Chemical Rescue A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two β-GlcNAcase homologs Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.Identification and analysis of catalytic TIM barrel domains in seven further glycoside hydrolase families.Characterization of a beta-N-acetylhexosaminidase and a beta-N-acetylglucosaminidase/beta-glucosidase from Cellulomonas fimi.High-throughput screening for human lysosomal beta-N-Acetyl hexosaminidase inhibitors acting as pharmacological chaperones.Biosynthesis of truncated N-linked oligosaccharides results from non-orthologous hexosaminidase-mediated mechanisms in nematodes, plants, and insects AutoMatch: target-binding protein design and enzyme design by automatic pinpointing potential active sites in available protein scaffolds.Crystal structure of β-hexosaminidase B in complex with pyrimethamine, a potential pharmacological chaperone Reaction mechanism of chitobiose phosphorylase from Vibrio proteolyticus: identification of family 36 glycosyltransferase in Vibrio.The Amazing Transglycosylation Activity of Endo-β-N-acetylglucosaminidases Substrate specificity of bacterial oligosaccharyltransferase suggests a common transfer mechanism for the bacterial and eukaryotic systems.Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family.Role of active-site residues of dispersin B, a biofilm-releasing beta-hexosaminidase from a periodontal pathogen, in substrate hydrolysis.Computational study of β-N-acetylhexosaminidase from Talaromyces flavus, a glycosidase with high substrate flexibility

P2860

Q24602248-A98C7424-BFB4-411E-A7D9-51050F22B99F Q24678311-2FC8D300-8313-4EF9-B36B-1279B67E8E0D Q27634351-F7AFD99C-1BF4-464E-ACF8-1A3BA40A1523 Q27634390-42711B77-1F6A-48D0-88FF-E5A6AE9F7623 Q27641402-63E8CC54-3F52-4AE7-81C5-54CF50B7475F Q27642397-D45D07B1-5488-4151-BB94-34E769AED2A2 Q27642554-92A7497D-6663-4CF3-BED9-C848A27BABE7 Q27652457-EE4467C9-A339-42D7-B2DA-0E37A37FE185 Q27655751-29DD3475-49C3-44C4-A6A1-0FAB326D1F65 Q27666054-8217DED5-F418-4B0B-B768-A616CE468943 Q27670493-2071D68A-8F2A-44D5-A331-A0BC624B2791 Q27675138-B8BA6BD1-304D-4A56-9DA9-359490D9D545 Q27675829-A70F598B-F97F-472A-A4F9-9800D2462B9A Q27676765-C612B9C0-6A84-44BE-BA0C-0320839673D6 Q27677503-EE804FCF-CEA4-42A9-9DA1-346263367CB8 Q27678337-25D40652-1A63-467A-B5A9-216876FFE23E Q27681140-5B7018BD-B8C2-42F5-A0EB-2680ACF4ECFA Q27687248-1970C1E9-E504-49D3-B76B-40B1E953C0CC Q27687260-E1CB4247-2E11-4166-85C3-FE2EC731C800 Q27695731-B6101B92-5E33-4D53-90BC-683C54FDCE46 Q27701904-9F7EAC6B-23F1-4B01-AE31-733AB3241A0F Q27708323-A8241F45-6417-4BB8-B1EC-B6B2DFD9145E Q28492135-7116104C-25AF-4159-A8F9-B9E9EF4E8673 Q28547650-AA311697-5DA2-40B5-AFC9-9CFC6A2405FB Q28550129-AC103452-3D04-41F8-807E-8598C8B2AF50 Q28550193-B43F32DF-D9C7-4805-9A6A-3A0B6E40FF98 Q28654269-BE7BA86B-A9EA-4E73-824F-F4741FE7492C Q30479533-C0A3069A-17E4-4F7B-A1A8-788600273454 Q33187248-70483F0C-0779-4177-8461-9ECBC3559E4C Q33246159-B766A97C-BF61-4BD5-A8A9-70DF6DF0819C Q33275131-247D425D-0D56-436C-9B44-1B152B6AAB6C Q33772071-0A0D8C4A-2821-4D77-93E6-DA23F6880D7D Q34121578-41B3AAA3-5C91-4079-B920-9F9E76EAFCAD Q34160716-EA18D25B-6A92-4250-8B6A-1FA8829456C1 Q34246820-ADEC5B18-0FEE-4CB5-A543-FE440C751B89 Q34314203-9A17CA91-B94B-429F-AC46-63996D32B368 Q34598569-8CF1FF0E-94B5-40FC-B328-AB8CC26D8646 Q34654335-FA17BAFD-4C42-4BAA-BE7C-7CE0FD87BB01 Q34703890-47130A23-AFA1-4EB5-9F25-60103EAE40C5 Q35258119-E380BC6D-1DB1-4372-BEC7-6B1B9B89E756

P2860

Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase

http://www.wikidata.org/entity/Q27629024

description

2001 nî lūn-bûn

@nan

2001 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի մարտին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@ast

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@en

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@nl

type

label

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@ast

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@en

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@nl

prefLabel

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@ast

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@en

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@nl

P1433

Q27629024-857DE9A7-ED38-488F-B32F-69B62DC887C5

P1476

Q27629024-D37E50B3-490B-4F4C-BF07-4429D050AEF5

P2093

Q27629024-5C0A6E6A-3D9A-4E7B-A4DC-1204A9B3BC6F

Q27629024-948759DF-35A8-48E9-9915-DE24639AD7B7

Q27629024-CDE7EA23-AF02-42C9-BB2C-EC69E2475DC9

P2860

Q27629024-0FB01F94-4CE3-4AC4-8877-779F450E0B40

Q27629024-16B58685-EA27-4FE0-8146-7CBACFBB04B8

Q27629024-1F3971CC-2676-43B4-AE3D-8484ED13D2C9

Q27629024-1FB05B70-236E-4AEF-92DA-F5D6EE1806A5

Q27629024-27EE67D6-DC86-4FC7-9BC4-E4AD48AC44A0

Q27629024-31773DF4-E6C8-4154-A4B2-B8DCFFA77AD7

Q27629024-32B56E50-DBE3-414A-A06F-E40A31D9CDC0

Q27629024-3397001C-FED9-4F18-A405-E91D0C8FB066

Q27629024-3DE6D4D6-1845-4F35-9E1B-609B8409E7EF

Q27629024-3E1824C6-03F6-4607-B074-29065336633D

P304

Q27629024-FC2F90DE-3096-42F5-821B-F6EE0F98B83B

P31

Q27629024-96FF9A29-5B7D-45D9-B130-B9053FBD573F

P3181

Q27629024-EA373C11-9F82-4D63-B217-08D15C889E1E

P356

Q27629024-8926399F-714A-4046-8590-12E681EC354A

P407

Q27629024-28BECE16-B26E-4F96-A2CF-FBA6E6D003C8

P433

Q27629024-59D736EF-7FD6-44CB-87E8-005C21DDE5C6

P478

Q27629024-6A43FE7D-650E-4918-9A3A-6FBE36D9CDEF

P50

Q27629024-28E1773A-57BD-4A8E-B30A-208B5931129A

Q27629024-A98FC453-4336-4F34-AC7B-C369097F2D9B

Q27629024-EA4981A1-F8C3-42E9-873C-1C34DDE2C4D4

P577

Q27629024-6DDDEC22-270E-4EC9-B2F6-4810372E7D9F

P5875

Q27629024-02DC8558-2968-4688-B95A-25F99BC2C46B

P698

Q27629024-ADFA325D-1367-4C40-92D9-3E3AA3DF810D

P3181

P356

P1433

Journal of Biological Chemistry

P1476

Crystallographic evidence for ...... bacterial beta-hexosaminidase

@en

P2093

James MN

http://www.w3.org/2001/XMLSchema#string

Knapp S

http://www.w3.org/2001/XMLSchema#string

Withers SG

http://www.w3.org/2001/XMLSchema#string

P2860

A classification of glycosyl hydrolases based on amino acid sequence similarities

New families in the classification of glycosyl hydrolases based on amino acid sequence similarities

Serratia marcescens chitobiase is a retaining glycosidase utilizing substrate acetamido group participation

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase

Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540

Stereochemistry of chitin hydrolysis by a plant chitinase/lysozyme and X-ray structure of a complex with allosamidin: evidence for substrate assisted catalysis

Structure of the 70-kDa soluble lytic transglycosylase complexed with bulgecin A. Implications for the enzymatic mechanism

P304

10330-10337

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1837506

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M011067200

http://www.w3.org/2001/XMLSchema#string

P407

P433

13

http://www.w3.org/2001/XMLSchema#string

P478

276

http://www.w3.org/2001/XMLSchema#string

P50

David J Vocadlo

Barbara Triggs-Raine

P577

2000-12-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12203860

http://www.w3.org/2001/XMLSchema#string

P698

11124970

http://www.w3.org/2001/XMLSchema#string