Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases
about
Three decades of beta-lactamase inhibitorsProbing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesisStructure-based optimization of cephalothin-analogue boronic acids as β-lactamase inhibitorsDesign, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase InhibitorsNovel Insights into the Mode of Inhibition of Class A SHV-1 -Lactamases Revealed by Boronic Acid Transition State InhibitorsIncreased Structural Flexibility at the Active Site of a Fluorophore-conjugated -Lactamase Distinctively Impacts Its Binding toward Diverse Cephalosporin AntibioticsCrystal Structure of a Preacylation Complex of the β-Lactamase Inhibitor Sulbactam Bound to a Sulfenamide Bond-Containing Thiol-β-lactamaseFragment-guided design of subnanomolar -lactamase inhibitors active in vivoAmino acid sequence determinants of extended spectrum cephalosporin hydrolysis by the class C P99 beta-lactamase.pKa measurements from nuclear magnetic resonance of tyrosine-150 in class C beta-lactamase.Identification of residues critical for catalysis in a class C beta-lactamase by combinatorial scanning mutagenesis.Saturation mutagenesis of Asn152 reveals a substrate selectivity switch in P99 cephalosporinaseInhibition of the class C beta-lactamase from Acinetobacter spp.: insights into effective inhibitor design.The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.Synthesis of amidomethyltrifluoroborates and their use in cross-coupling reactionsStructure, function, and inhibition along the reaction coordinate of CTX-M beta-lactamases.Exploring sequence requirements for C₃/C₄ carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase.Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors.Fragment-based inhibitor discovery against β-lactamaseInteractions of oximino-substituted boronic acids and β-lactams with the CMY-2-derived extended-spectrum cephalosporinases CMY-30 and CMY-42Structure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell cultureInteractions of "bora-penicilloates" with serine β-lactamases and DD-peptidasesProbing active site chemistry in SHV beta-lactamase variants at Ambler position 244. Understanding unique properties of inhibitor resistance.Tackling the Antibiotic Resistance Caused by Class A -Lactamases through the Use of -Lactamase Inhibitory ProteinCovalent docking of selected boron-based serine beta-lactamase inhibitors
P2860
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P2860
Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Energetic, structural, and ant ...... recognition by beta-lactamases
@ast
Energetic, structural, and ant ...... recognition by beta-lactamases
@en
Energetic, structural, and ant ...... recognition by beta-lactamases
@nl
type
label
Energetic, structural, and ant ...... recognition by beta-lactamases
@ast
Energetic, structural, and ant ...... recognition by beta-lactamases
@en
Energetic, structural, and ant ...... recognition by beta-lactamases
@nl
prefLabel
Energetic, structural, and ant ...... recognition by beta-lactamases
@ast
Energetic, structural, and ant ...... recognition by beta-lactamases
@en
Energetic, structural, and ant ...... recognition by beta-lactamases
@nl
P2093
P1476
Energetic, structural, and ant ...... recognition by beta-lactamases
@en
P2093
P356
10.1016/S1074-5521(00)00052-1
P577
2001-01-01T00:00:00Z