High resolution structural analyses of mutant chitinase A complexes with substrates provide new insight into the mechanism of catalysis
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Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytesStructure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectinsStructural Basis for Broad Substrate Specificity in Higher Plant beta-D-Glucan GlucohydrolasesHigh-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: mimicry of carbohydrate substrateThe cyclic dipeptide CI-4 [cyclo-(l-Arg-d-Pro)] inhibits family 18 chitinases by structural mimicry of a reaction intermediateCrystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39Family 18 chitinase–oligosaccharide substrate interaction: subsite preference and anomer selectivity of Serratia marcescens chitinase AThree-dimensional structure of the barley beta-D-glucan glucohydrolase in complex with a transition state mimicKinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active siteFully Deacetylated Chitooligosaccharides Act as Efficient Glycoside Hydrolase Family 18 Chitinase InhibitorsStructure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacteriumStructure of chitinase D from Serratia proteamaculans reveals the structural basis of its dual action of hydrolysis and transglycosylationCrystal structures of substrate-bound chitinase from the psychrophilic bacterium Moritella marina and its structure in solutionNew insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MMStructural and functional analysis of SleL, a peptidoglycan lysin involved in germination of Bacillus sporesSequence and structural analysis of the chitinase insertion domain reveals two conserved motifs involved in chitin-bindingCrystal Structure of Chitinase ChiW from Paenibacillus sp. str. FPU-7 Reveals a Novel Type of Bacterial Cell-Surface-Expressed Multi-Modular Enzyme MachineryA holin and an endopeptidase are essential for chitinolytic protein secretion in Serratia marcescens.A new chitinase-like xylanase inhibitor protein (XIP) from coffee (Coffea arabica) affects Soybean Asian rust (Phakopsora pachyrhizi) spore germinationChitinase gene sequences retrieved from diverse aquatic habitats reveal environment-specific distributions.Molecular docking and site-directed mutagenesis of a Bacillus thuringiensis chitinase to improve chitinolytic, synergistic lepidopteran-larvicidal and nematicidal activities.Expression, purification, crystallization and preliminary crystallographic analysis of chitinase A from Vibrio carchariaeSph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatusChemoenzymatic synthesis of N-linked neoglycoproteins through a chitinase-catalyzed transglycosylation.Characterization of two novel bacterial type A exo-chitobiose hydrolases having C-terminal 5/12-type carbohydrate-binding modules.Expression and characterization of endochitinase C from Serratia marcescens BJL200 and its purification by a one-step general chitinase purification method.The predominant molecular state of bound enzyme determines the strength and type of product inhibition in the hydrolysis of recalcitrant polysaccharides by processive enzymesAnalysis of productive binding modes in the human chitotriosidase.Mutation of a conserved tryptophan in the chitin-binding cleft of Serratia marcescens chitinase A enhances transglycosylation.Endo/exo mechanism and processivity of family 18 chitinases produced by Serratia marcescens.Aromatic residues within the substrate-binding cleft of Bacillus circulans chitinase A1 are essential for hydrolysis of crystalline chitin.Cloning, Site-Directed Mutagenesis, and Functional Analysis of Active Residues in Lymantria dispar Chitinase.Characterization of two Listeria innocua chitinases of different sizes that were expressed in Escherichia coli.Aromatic residues in the catalytic center of chitinase A from Serratia marcescens affect processivity, enzyme activity, and biomass converting efficiency.Slow Off-rates and Strong Product Binding Are Required for Processivity and Efficient Degradation of Recalcitrant Chitin by Family 18 ChitinasesAzide anions inhibit GH-18 endochitinase and GH-20 Exo β-N-acetylglucosaminidase from the marine bacterium Vibrio harveyi.Preparation of the methyl ester of hyaluronan and its enzymatic degradationMutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase.Kinetic evidence related to substrate-assisted catalysis of family 18 chitinases.Overexpression, purification, and characterization of Paenibacillus cell surface-expressed chitinase ChiW with two catalytic domains.
P2860
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P2860
High resolution structural analyses of mutant chitinase A complexes with substrates provide new insight into the mechanism of catalysis
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
High resolution structural ana ...... nto the mechanism of catalysis
@ast
High resolution structural ana ...... nto the mechanism of catalysis
@en
High resolution structural ana ...... nto the mechanism of catalysis
@nl
type
label
High resolution structural ana ...... nto the mechanism of catalysis
@ast
High resolution structural ana ...... nto the mechanism of catalysis
@en
High resolution structural ana ...... nto the mechanism of catalysis
@nl
prefLabel
High resolution structural ana ...... nto the mechanism of catalysis
@ast
High resolution structural ana ...... nto the mechanism of catalysis
@en
High resolution structural ana ...... nto the mechanism of catalysis
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P2093
P356
P1433
P1476
High resolution structural ana ...... nto the mechanism of catalysis
@en
P2093
A B Oppenheim
C E Vorgias
Y Papanikolau
P304
11338-11343
P356
10.1021/BI010505H
P407
P50
P577
2001-09-01T00:00:00Z