Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds
about
The yeast prion protein Ure2 shows glutathione peroxidase activity in both native and fibrillar forms.Alterations in the Ure2 αCap domain elicit different GATA factor responses to rapamycin treatment and nitrogen limitationStructure of the prion Ure2p in protein fibrils assembled in vitro.Yeast prions assembly and propagation: contributions of the prion and non-prion moieties and the nature of assemblies.Amyloid-like aggregates of the yeast prion protein ure2 enter vertebrate cells by specific endocytotic pathways and induce apoptosis.The yeast prion Ure2p retains its native alpha-helical conformation upon assembly into protein fibrils in vitroPrions: En route from structural models to structures.Cellular responses to mitochondrial dysfunction: it's not always downhill.Ure2, a prion precursor with homology to glutathione S-transferase, protects Saccharomyces cerevisiae cells from heavy metal ion and oxidant toxicity.Functional diversification of fungal glutathione transferases from the ure2p classPropagation of yeast prions.Molecular chaperones and the assembly of the prion Ure2p in vitro.Ure2p function is enhanced by its prion domain in Saccharomyces cerevisiae.Prions in yeast.Insights into the architecture of the Ure2p yeast protein assemblies from helical twisted fibrilsInfluence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2Recent advances in nitrogen regulation: a comparison between Saccharomyces cerevisiae and filamentous fungiNovel glutaredoxin activity of the yeast prion protein Ure2 reveals a native-like dimer within fibrilsSynthetic lipid vesicles recruit native-like aggregates and affect the aggregation process of the prion Ure2p: insights on vesicle permeabilization and charge selectivity.A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance.The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless of their aggregation state.Expression, purification, crystallization and structure determination of two glutathione S-transferase-like proteins from Shewanella oneidensis.Structural basis for the function of stringent starvation protein a as a transcription factor.Architecture of Ure2p prion filaments: the N-terminal domains form a central core fiber.In vivo specificity of Ure2 protection from heavy metal ion and oxidative cellular damage in Saccharomyces cerevisiae.The role of an evolutionarily conserved cis-proline in the thioredoxin-like domain of human class Alpha glutathione transferase A1-1.Nitrogen-source regulation of yeast gamma-glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3.Structure-function relationships in glutathione and its analogues.Characterization of oligomeric species in the fibrillization pathway of the yeast prion Ure2p.In vitro analysis of SpUre2p, a prion-related protein, exemplifies the relationship between amyloid and prion.Three distinct-type glutathione S-transferases from Escherichia coli important for defense against oxidative stress.
P2860
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P2860
Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Crystal structures of the yeas ...... tathione and related compounds
@ast
Crystal structures of the yeas ...... tathione and related compounds
@en
Crystal structures of the yeas ...... tathione and related compounds
@nl
type
label
Crystal structures of the yeas ...... tathione and related compounds
@ast
Crystal structures of the yeas ...... tathione and related compounds
@en
Crystal structures of the yeas ...... tathione and related compounds
@nl
prefLabel
Crystal structures of the yeas ...... tathione and related compounds
@ast
Crystal structures of the yeas ...... tathione and related compounds
@en
Crystal structures of the yeas ...... tathione and related compounds
@nl
P2093
P356
P1433
P1476
Crystal structures of the yeas ...... tathione and related compounds
@en
P2093
P304
P356
10.1021/BI011007B
P407
P577
2001-11-13T00:00:00Z