Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics
about
The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificitiesCrystal structure of PTP1B complexed with a potent and selective bidentate inhibitorProtein tyrosine phosphatase 1B: a new target for the treatment of obesity and associated co-morbidities.Recent advances in protein tyrosine phosphatase 1B inhibitors.Design, synthesis, and evaluation of 2-(arylsulfonyl)oxiranes as cell-permeable covalent inhibitors of protein tyrosine phosphatases.Druggability analysis and classification of protein tyrosine phosphatase active sites.Structure based design of compounds from natural sources for diabetes and inflammation.Structure-based design of selective and potent inhibitors of protein-tyrosine phosphatase beta.Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor.Prediction of enzyme inhibition and mode of inhibitory action based on calculation of distances between hydrogen bond donor/acceptor groups of the molecule and docking analysis: An application on the discovery of novel effective PTP1B inhibitors.Efficiency of alchemical free energy simulations. I. A practical comparison of the exponential formula, thermodynamic integration, and Bennett's acceptance ratio method.Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.
P2860
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P2860
Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@ast
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@en
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@nl
type
label
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@ast
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@en
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@nl
prefLabel
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@ast
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@en
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@nl
P2093
P3181
P356
P1476
Structure of protein tyrosine ...... g two phosphotyrosine mimetics
@en
P2093
A N Dinaut
C Ramachandran
D Waddleton
S D Taylor
P304
P3181
P356
10.1021/JM010266W
P407
P577
2001-12-20T00:00:00Z