Structural basis for the activation of human procaspase-7 - Wikidata - awgldk - TriplyDB

Structural basis for the activation of human procaspase-7

Structural basis for the activation of human procaspase-7

http://www.wikidata.org/entity/Q27636985

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Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3 A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activation Crystal structure of an invertebrate caspase Crystal Structure of Procaspase-1 Zymogen Domain Reveals Insight into Inflammatory Caspase Autoactivation Mechanism of procaspase-8 activation by c-FLIPL L2′ loop is critical for caspase-7 active site formation Substrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6 Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.A designed redox-controlled caspase A Class of Allosteric Caspase Inhibitors Identified by High-Throughput Screening Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7 Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation Allosteric modulation of caspase 3 through mutagenesis Mechanistic insights into CED-4-mediated activation of CED-3 Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization Structural asymmetry of procaspase-7 bound to a specific inhibitor Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats Emergence of FGFR family gene fusions as therapeutic targets in a wide spectrum of solid tumours Molecular mechanisms of caspase regulation during apoptosis Discovery of an allosteric site in the caspases A multi-factor model for caspase degradome prediction Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine.Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members.Mechanism and specificity of the human paracaspase MALT1.Activation of caspases-8 and -10 by FLIP(L).A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases.Human caspases: activation, specificity, and regulation Different apoptotic effects of [Pt(O,O'-acac)(γ-acac)(DMS)] and cisplatin on normal and cancerous human epithelial breast cells in primary culture Caspases on the brain.Mutations in the procaspase-3 dimer interface affect the activity of the zymogen.Reassembly of active caspase-3 is facilitated by the propeptide.Targeting cell death in tumors by activating caspases.An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3.

P2860

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P2860

Structural basis for the activation of human procaspase-7

http://www.wikidata.org/entity/Q27636985

description

2001 nî lūn-bûn

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2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Structural basis for the activation of human procaspase-7

@ast

Structural basis for the activation of human procaspase-7

@en

Structural basis for the activation of human procaspase-7

@nl

type

label

Structural basis for the activation of human procaspase-7

@ast

Structural basis for the activation of human procaspase-7

@en

Structural basis for the activation of human procaspase-7

@nl

prefLabel

Structural basis for the activation of human procaspase-7

@ast

Structural basis for the activation of human procaspase-7

@en

Structural basis for the activation of human procaspase-7

@nl

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Structural basis for the activation of human procaspase-7

@en

P2093

G S Salvesen

http://www.w3.org/2001/XMLSchema#string

M Renatus

http://www.w3.org/2001/XMLSchema#string

N Kairies

http://www.w3.org/2001/XMLSchema#string

P Fuentes-Prior

http://www.w3.org/2001/XMLSchema#string

R Huber

http://www.w3.org/2001/XMLSchema#string

S J Riedl

http://www.w3.org/2001/XMLSchema#string

S Krapp

http://www.w3.org/2001/XMLSchema#string

W Bode

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis of caspase-7 inhibition by XIAP

Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain

Structural basis for the inhibition of caspase-3 by XIAP

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

PROCHECK: a program to check the stereochemical quality of protein structures

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

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14790-5

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scholarly article

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10.1073/PNAS.221580098

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P433

26

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98

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2001-12-18T00:00:00Z

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11605749

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11752425

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64937

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