Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity
about
Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase familyAffinity alkylation of the Trp-B4 residue of the beta -subunit of the glutaryl 7-aminocephalosporanic acid acylase of Pseudomonas sp. 130Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallographyStructure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activityEvolution of an acylase active on cephalosporin CA highly active adipyl-cephalosporin acylase obtained via rational randomization.Improving the activity and stability of GL-7-ACA acylase CA130 by site-directed mutagenesis.The N-terminal nucleophile serine of cephalosporin acylase executes the second autoproteolytic cleavage and acylpeptide hydrolysisEnzymatic modifications of cephalosporins by cephalosporin acylase and other enzymes.Cephalosporin C acylase: dream and(/or) reality.Improvement of the glutaryl-7-aminocephalosporanic acid acylase activity of a bacterial gamma-glutamyltranspeptidase.Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens.Alteration of substrate selection of antibiotic acylase from β-lactam to echinocandin.Overexpression of penicillin V acylase from Streptomyces lavendulae and elucidation of its catalytic residues.Systematic optimization model and algorithm for binding sequence selection in computational enzyme design.Altering the substrate specificity of cephalosporin acylase by directed evolution of the Beta -subunit.Directed evolution of a glutaryl acylase into an adipyl acylase.A bound water molecule is crucial in initiating autocatalytic precursor activation in an N-terminal hydrolase.Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase.Evaluation of active designs of cephalosporin C acylase by molecular dynamics simulation and molecular docking.Strategic manipulation of an industrial biocatalyst--evolution of a cephalosporin C acylase
P2860
Q27636180-8EDF634E-4B66-4B26-A7A9-2B847995A836Q27637222-C17C879C-3A87-43D2-ACBF-E5CDC7EBEE02Q27657154-3AE7CFA3-DC50-412E-A876-5CEB51B3707AQ27683865-4D215B7A-B32B-4372-ADFA-840BD0C5E709Q33226329-345A24CE-BB50-4CBA-911F-58DCD4F9F0F6Q33301949-3E0BB696-28F5-4B33-B346-5978F8B18126Q33995892-44577B7C-EA7B-450B-9840-E7A8609681AEQ35085191-23DCFCEC-4647-4E5F-A516-8954CDBDCB8AQ36523466-5F2A56EA-25F3-48EC-B0E9-97EB3669428BQ38082383-BDE19FF3-DD0A-4FB7-BB50-94FABF50F543Q39022808-C81C10BB-E738-41D5-B7D0-C04A7B7CB0DFQ39392982-9DC3A040-B350-4B15-BA97-6AEC5FE5882CQ40294313-3799E75B-2277-43A0-BE0A-EFD73C742115Q41697614-2EBCD23E-6B98-407F-A39A-0EFF59D11937Q43080927-1DA2DD4E-3C99-4214-AC2B-6D91B32D8C10Q44116156-5A76FB27-B5CA-4B9E-8021-BD1524EA02BDQ44135941-6DDEBC9B-D5B0-423E-9E24-0FC17178A1FFQ44610979-605F3013-E6B7-4714-BB2A-F55DB12BA15DQ44918705-36FF2DCF-B09A-4DD2-AAA2-9B4C1AC31092Q53523989-9CA1131C-372A-480D-9C2C-6822552C4E62Q56894003-2BF77172-D92F-4CE3-90A1-305DA4E9A789
P2860
Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structure of cephalosporin acy ...... s of its substrate specificity
@ast
Structure of cephalosporin acy ...... s of its substrate specificity
@en
Structure of cephalosporin acy ...... s of its substrate specificity
@nl
type
label
Structure of cephalosporin acy ...... s of its substrate specificity
@ast
Structure of cephalosporin acy ...... s of its substrate specificity
@en
Structure of cephalosporin acy ...... s of its substrate specificity
@nl
prefLabel
Structure of cephalosporin acy ...... s of its substrate specificity
@ast
Structure of cephalosporin acy ...... s of its substrate specificity
@en
Structure of cephalosporin acy ...... s of its substrate specificity
@nl
P1476
Structure of cephalosporin acy ...... s of its substrate specificity
@en
P304
P356
10.1016/S1074-5521(01)00092-8
P577
2001-12-01T00:00:00Z