A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex
about
Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseEvolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.To affinity and beyond: harnessing the T cell receptor for cancer immunotherapySurface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivityA T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I moleculeHow much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'Structures of MART-126/27–35 Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell RecognitionSingle MHC Mutation Eliminates Enthalpy Associated with T Cell Receptor BindingHow a T Cell Receptor-like Antibody Recognizes Major Histocompatibility Complex-bound PeptideDistinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientationConformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificityA Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR ConformersStructural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptorCrossreactivity of a human autoimmune TCR is dominated by a single TCR loopWhat Is Direct Allorecognition?T cells and their eons-old obsession with MHCStructural basis of affinity maturation and intramolecular cooperativity in a protein-protein interactionDynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles.The effect of mutations on the alloreactive T cell receptor/peptide-MHC interface structure: a molecular dynamics study.An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role.Understanding TR binding to pMHC complexes: how does a TR scan many pMHC complexes yet preferentially bind to one.TCRep 3D: an automated in silico approach to study the structural properties of TCR repertoires.Interaction pattern of Arg 62 in the A-pocket of differentially disease-associated HLA-B27 subtypes suggests distinct TCR binding modes.Evolving concepts of specificity in immune reactionsA conformational change senses the strength of T cell receptor-ligand interaction during thymic selection.Vgamma2Vdelta2 T Cell Receptor recognition of prenyl pyrophosphates is dependent on all CDRsT cell receptor recognition of self and foreign antigens in the induction of autoimmunity.T cell receptor-ligand interactions: a conformational preequilibrium or an induced fit.Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction.Quantitative Analysis of the Association Angle between T-cell Receptor Vα/Vβ Domains Reveals Important Features for Epitope RecognitionMolecular analysis of TCR and peptide/MHC interaction using P18-I10-derived peptides with a single D-amino acid substitution.T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytesA comprehensive calorimetric investigation of an entropically driven T cell receptor-peptide/major histocompatibility complex interaction.The Dynamics of the Human Leukocyte Antigen Head Domain Modulates Its Recognition by the T-Cell Receptor.Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptorThe TCR binding site does moveSpatial coordination of CD8 and TCR molecules controls antigen recognition by CD8+ T-cells.Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.Unusual features of self-peptide/MHC binding by autoimmune T cell receptors
P2860
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P2860
A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@ast
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@en
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@nl
type
label
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@ast
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@en
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@nl
prefLabel
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@ast
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@en
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@nl
P2093
P50
P3181
P1433
P1476
A T cell receptor CDR3beta loo ...... a peptide/MHC class I complex
@en
P2093
Annick Guimezanes
Claude Grégoire
Claudine Darnault
Dominique Housset
Gilbert Mazza
Juan Carlos Fontecilla-Camps
Thomas Mosser
P304
P3181
P356
10.1016/S1074-7613(02)00288-1
P407
P577
2002-03-01T00:00:00Z