Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity
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Phosphofructokinase 1 glycosylation regulates cell growth and metabolismMolecular cloning and characterization of a novel human beta 1,4-N-acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAcExploring the O-GlcNAc proteome: direct identification of O-GlcNAc-modified proteins from the brainStrategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer TherapeuticsStructural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motifStructural Analysis of Thermus thermophilus HB27 Mannosyl-3-phosphoglycerate Synthase Provides Evidence for a Second Catalytic Metal Ion and New Insight into the Retaining Mechanism of GlycosyltransferasesSite-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 1: Cysteine Residues and GlycansCurrent Status: Site-Specific Antibody Drug ConjugatesStructure-based evolutionary relationship of glycosyltransferases: a case study of vertebrate β1,4-galactosyltransferase, invertebrate β1,4-N-acetylgalactosaminyltransferase and α-polypeptidyl-N-acetylgalactosaminyltransferaseDirect identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic methodSite specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detectionQuantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags.Beta-N-acetylglucosamine (O-GlcNAc) is part of the histone codeA single point mutation in the gene encoding Gb3/CD77 synthase causes a rare inherited polyagglutination syndrome.O-GlcNAcylation: a novel post-translational mechanism to alter vascular cellular signaling in health and disease: focus on hypertension.Improved synthesis of UDP-2-(2-ketopropyl)galactose and a first synthesis of UDP-2-(2-ketopropyl)glucose for the site-specific linking of biomolecules via modified glycan residues using glycosyltransferasesBiochemical characterization and membrane topology of Alg2 from Saccharomyces cerevisiae as a bifunctional alpha1,3- and 1,6-mannosyltransferase involved in lipid-linked oligosaccharide biosynthesis.Reversible hydrazide chemistry-based enrichment for O-GlcNAc-modified peptides and glycopeptides having non-reducing GlcNAc residues.Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug developmentGenetic, biochemical, and serological characterization of a new pneumococcal serotype, 6H, and generation of a pneumococcal strain producing three different capsular repeat units.Site-specific antibody-drug conjugation through an engineered glycotransferase and a chemically reactive sugarChemical approaches to understanding O-GlcNAc glycosylation in the brain.The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2.Role of a single amino acid in the evolution of glycans of invertebrates and vertebratesMultiple site-specific in vitro labeling of single-chain antibodyBioconjugation and detection of lactosamine moiety using alpha1,3-galactosyltransferase mutants that transfer C2-modified galactose with a chemical handle.Novel UDP-GalNAc Derivative Structures Provide Insight into the Donor Specificity of Human Blood Group Glycosyltransferase.Mutant glycosyltransferases assist in the development of a targeted drug delivery system and contrast agents for MRIApplications of glycosyltransferases in the site-specific conjugation of biomolecules and the development of a targeted drug delivery system and contrast agents for MRI.Use of novel mutant galactosyltransferase for the bioconjugation of terminal N-acetylglucosamine (GlcNAc) residues on live cell surfaceStructure and function of beta -1,4-galactosyltransferaseSite-specific linking of biomolecules via glycan residues using glycosyltransferases.Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitorsComprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tagStreptococcus pneumoniae serotype 11D has a bispecific glycosyltransferase and expresses two different capsular polysaccharide repeating units.Site-specific GlcNAcylation of human erythrocyte proteins: potential biomarker(s) for diabetes.Discovery of Streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units.The chemical neurobiology of carbohydratesPretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate.A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer.
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P2860
Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@ast
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@en
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@nl
type
label
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@ast
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@en
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@nl
prefLabel
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@ast
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@en
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@nl
P2860
P3181
P356
P1476
Structure-based design of beta ...... beta 4Gal-T1 donor specificity
@en
P2093
Boopathy Ramakrishnan
Pradman K Qasba
P2860
P304
P3181
P356
10.1074/JBC.M111183200
P407
P577
2002-06-07T00:00:00Z