Kinetic and structural basis of reactivity of pentaerythritol tetranitrate reductase with NADPH, 2-cyclohexenone, nitroesters, and nitroaromatic explosives
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Crystal structure of bacterial morphinone reductase and properties of the C191A mutant enzymeExpansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesisA site-saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivityCrystallization and preliminary analysis of active nitroalkane oxidase in three crystal formsStructural and Mechanistic Insights into the Pseudomonas fluorescens 2-Nitrobenzoate 2-Nitroreductase NbaAIdentification of peptide sequences that selectively bind to pentaerythritol trinitrate hemisuccinate-a surrogate of PETN, via phage display technology.Reduction of polynitroaromatic compounds: the bacterial nitroreductases.Structure-Based Insight into the Asymmetric Bioreduction of the C=C Double Bond of alpha,beta-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase.Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation.Nicotinamide-independent asymmetric bioreduction of CC-bonds via disproportionation of enones catalyzed by enoate reductases.Understanding the broad substrate repertoire of nitroreductase based on its kinetic mechanism.Nanofibrillar Peptide hydrogels for the immobilization of biocatalysts for chemical transformations.Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding.Towards structural studies of the old yellow enzyme homologue SYE4 from Shewanella oneidensis and its complexes at atomic resolution.Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase.H-tunneling in the multiple H-transfers of the catalytic cycle of morphinone reductase and in the reductive half-reaction of the homologous pentaerythritol tetranitrate reductase.Atomic resolution structures and solution behavior of enzyme-substrate complexes of Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase. Multiple conformational states and implications for the mechanism of nitroaromatic explosive degradaReaction of morphinone reductase with 2-cyclohexen-1-one and 1-nitrocyclohexene: proton donation, ligand binding, and the role of residues Histidine 186 and Asparagine 189.Gas phase reactions of 1,3,5-triazine: proton transfer, hydride transfer, and anionic σ-adduct formation.Reduction of aliphatic nitroesters and N-nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships.Proteomic Analysis of 2,4,6-Trinitrotoluene Degrading Yeast Yarrowia lipolytica.(1)H, (15)N and (13)C backbone resonance assignments of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2.Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands.A surprising observation that oxygen can affect the product enantiopurity of an enzyme-catalysed reactionActive site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with α,β-unsaturated nitroolefins
P2860
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P2860
Kinetic and structural basis of reactivity of pentaerythritol tetranitrate reductase with NADPH, 2-cyclohexenone, nitroesters, and nitroaromatic explosives
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Kinetic and structural basis o ...... , and nitroaromatic explosives
@ast
Kinetic and structural basis o ...... , and nitroaromatic explosives
@en
Kinetic and structural basis o ...... , and nitroaromatic explosives
@nl
type
label
Kinetic and structural basis o ...... , and nitroaromatic explosives
@ast
Kinetic and structural basis o ...... , and nitroaromatic explosives
@en
Kinetic and structural basis o ...... , and nitroaromatic explosives
@nl
prefLabel
Kinetic and structural basis o ...... , and nitroaromatic explosives
@ast
Kinetic and structural basis o ...... , and nitroaromatic explosives
@en
Kinetic and structural basis o ...... , and nitroaromatic explosives
@nl
P2093
P2860
P356
P1476
Kinetic and structural basis o ...... , and nitroaromatic explosives
@en
P2093
Daniel H Craig
Neil C Bruce
Nigel S Scrutton
Richard J Harris
Terez Barna
P2860
P304
21906-21912
P356
10.1074/JBC.M200637200
P407
P577
2002-03-28T00:00:00Z