Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates
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Evidence for a high-spin Fe(IV) species in the catalytic cycle of a bacterial phenylalanine hydroxylaseMechanism of aromatic amino acid hydroxylationStructure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H, a monomeric cold active enzyme with local flexibility around the active site and high overall stabilityAn additional substrate binding site in a bacterial phenylalanine hydroxylaseStructural and thermodynamic insight into phenylalanine hydroxylase from the human pathogenLegionella pneumophilaFolding dynamics of phenylalanine hydroxylase depends on the enzyme's metallation state: the native metal, iron, protects against aggregate intermediates.Detection of protein catalytic residues at high precision using local network properties.Chlamydia pneumoniae encodes a functional aromatic amino acid hydroxylase.Formation of the iron-oxo hydroxylating species in the catalytic cycle of aromatic amino acid hydroxylases.Phenylalanine hydroxylase from Legionella pneumophila is a thermostable enzyme with a major functional role in pyomelanin synthesis.A conserved acidic residue in phenylalanine hydroxylase contributes to cofactor affinity and catalysis.Dynamic regulation of phenylalanine hydroxylase by simulated redox manipulationRole of the phenylalanine-hydroxylating system in aromatic substance degradation and lipid metabolism in the oleaginous fungus Mortierella alpinaDisruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphidsp-Cresyl Sulfate.Bioinformatics in bioinorganic chemistry.Allosteric regulation of phenylalanine hydroxylase.Phenylalanine hydroxylase: function, structure, and regulation.Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine.Measurement of the intramolecular isotope effect on aliphatic hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase.Heme protein and hydroxyarginase necessary for biosynthesis of D-cycloserineIdentification of phenylalanine 3-hydroxylase for meta-tyrosine biosynthesis.Kinetic isotope effects on aromatic and benzylic hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase as probes of chemical mechanism and reactivity.Reevaluation of the violacein biosynthetic pathway and its relationship to indolocarbazole biosynthesis.
P2860
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P2860
Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structural comparison of bacte ...... t stability and reaction rates
@ast
Structural comparison of bacte ...... t stability and reaction rates
@en
Structural comparison of bacte ...... t stability and reaction rates
@nl
type
label
Structural comparison of bacte ...... t stability and reaction rates
@ast
Structural comparison of bacte ...... t stability and reaction rates
@en
Structural comparison of bacte ...... t stability and reaction rates
@nl
prefLabel
Structural comparison of bacte ...... t stability and reaction rates
@ast
Structural comparison of bacte ...... t stability and reaction rates
@en
Structural comparison of bacte ...... t stability and reaction rates
@nl
P2093
P3181
P1476
Structural comparison of bacte ...... t stability and reaction rates
@en
P2093
Alon Volner
Andrew Han
Heidi Erlandsen
Mahdi M Abu-Omar
Marianne G Patch
Raymond C Stevens
P304
P3181
P356
10.1016/S0022-2836(02)00496-5
P407
P577
2002-07-12T00:00:00Z