Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA
about
SecA, a remarkable nanomachinePreprotein-controlled catalysis in the helicase motor of SecAProtein translocation: what's the problem?Channel crossing: how are proteins shipped across the bacterial plasma membrane?Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPaseStructural determinants of SecB recognition by SecA in bacterial protein translocationStructural Basis for Signal-Sequence Recognition by the Translocase Motor SecA as Determined by NMRConformational transition of Sec machinery inferred from bacterial SecYE structuresConformational Flexibility and Peptide Interaction of the Translocation ATPase SecAATPase Active-Site Electrostatic Interactions Control the Global Conformation of the 100 kDa SecA TranslocaseThe conformation of a signal peptide bound by Escherichia coli preprotein translocase SecAATPase activity of Mycobacterium tuberculosis SecA1 and SecA2 proteins and its importance for SecA2 function in macrophagesSecA, the motor of the secretion machine, binds diverse partners on one interactive surface.Sites of interaction of a precursor polypeptide on the export chaperone SecB mapped by site-directed spin labeling.Orientation of SecA and SecB in complex, derived from disulfide cross-linkingThe oligomeric state and arrangement of the active bacterial transloconA large conformational change of the translocation ATPase SecASecA-dependent quality control of intracellular protein localization.Loss of outer membrane proteins without inhibition of lipid export in an Escherichia coli YaeT mutant.Use of synthetic signal sequences to explore the protein export machinery.Crystal structure of the human ATP-dependent splicing and export factor UAP56.A novel strategy to improve protein secretion via overexpression of the SppA signal peptide peptidase in Bacillus licheniformisAnalysis of SecA dimerization in solution.Mapping of the signal peptide-binding domain of Escherichia coli SecA using Förster resonance energy transfer.Dimeric SecA is essential for protein translocation.SecM facilitates translocase function of SecA by localizing its biosynthesisConditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function.Target-directed proteolysis at the ribosome.Structure and function of the bacterial Sec translocon.The structural view of bacterial translocation-specific chaperone SecB: implications for function.A novel class of secA alleles that exert a signal-sequence-dependent effect on protein export in Escherichia coli.Energetics of SecA dimerization.Nucleotide binding induces changes in the oligomeric state and conformation of Sec A in a lipid environment: a small-angle neutron-scattering study.Mapping of the SecA signal peptide binding site and dimeric interface by using the substituted cysteine accessibility methodRing-like pore structures of SecA: implication for bacterial protein-conducting channels.Probing the affinity of SecA for signal peptide in different environments.The basis of asymmetry in the SecA:SecB complex.Molecular engineering of secretory machinery components for high-level secretion of proteins in Bacillus species.Intraribosomal regulation of expression and fate of proteins.Proteins Related to the Type I Secretion System Are Associated with Secondary SecA_DEAD Domain Proteins in Some Species of Planctomycetes, Verrucomicrobia, Proteobacteria, Nitrospirae and Chlorobi
P2860
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P2860
Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Nucleotide control of interdom ...... ational reaction cycle of SecA
@ast
Nucleotide control of interdom ...... ational reaction cycle of SecA
@en
Nucleotide control of interdom ...... ational reaction cycle of SecA
@nl
type
label
Nucleotide control of interdom ...... ational reaction cycle of SecA
@ast
Nucleotide control of interdom ...... ational reaction cycle of SecA
@en
Nucleotide control of interdom ...... ational reaction cycle of SecA
@nl
prefLabel
Nucleotide control of interdom ...... ational reaction cycle of SecA
@ast
Nucleotide control of interdom ...... ational reaction cycle of SecA
@en
Nucleotide control of interdom ...... ational reaction cycle of SecA
@nl
P2093
P3181
P356
P1433
P1476
Nucleotide control of interdom ...... ational reaction cycle of SecA
@en
P2093
Donald B Oliver
John F Hunt
John J Fak
Lisa Henry
Paul McNicholas
Sevil Weinkauf
P304
P3181
P356
10.1126/SCIENCE.1074424
P407
P577
2002-09-20T00:00:00Z