Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity
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A post-translational modification of nuclear proteins, N(G),N(G)-dimethyl-Arg, found in a natural HLA class I peptide ligandTypes of inter-atomic interactions at the MHC-peptide interface: identifying commonality from accumulated dataChallenges in Antibody Development against Tn and Sialyl-Tn AntigensCarbohydrate-mimetic peptides for pan anti-tumor responsesStructural analysis of mycobacterial and murine hsp60 epitopes in complex with the class I MHC molecule H-2DbDiscovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramersIdentification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia.The molecular basis of CD1-mediated presentation of lipid antigens.Bridging innate and adaptive antitumor immunity targeting glycans.Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responsesProcessing of glycans on glycoprotein and glycopeptide antigens in antigen-presenting cellsFunction-related regulation of the stability of MHC proteins.A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor.Tumor-Associated Glycans and Immune SurveillanceThe optimization of peptide cargo bound to MHC class I molecules by the peptide-loading complex.Structure-based prediction of binding peptides to MHC class I molecules: application to a broad range of MHC allelesComplex carbohydrates are not removed during processing of glycoproteins by dendritic cells: processing of tumor antigen MUC1 glycopeptides for presentation to major histocompatibility complex class II-restricted T cellsIdentification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes.MUC1 immunotherapy.Carbohydrates as T-cell antigens with implications in health and disease.The Tat-conjugated N-terminal region of mucin antigen 1 (MUC1) induces protective immunity against MUC1-expressing tumours.O-glycosylated versus non-glycosylated MUC1-derived peptides as potential targets for cytotoxic immunotherapy of carcinoma.High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance.N-linked carbohydrates in tyrosinase are required for its recognition by human MHC class II-restricted CD4(+) T cells.Synthesis of β-C-GlcNAc Ser from β-C-Glc Ser.Shared structural motifs in TCR of glycopeptide-recognizing T cell hybridomas.Presentation of cytosolic glycosylated peptides by human class I major histocompatibility complex molecules in vivo.Immunization with a carbohydrate mimicking peptide augments tumor-specific cellular responses.Structural definition of the H-2Kd peptide-binding motif.Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate.Altered immunogenicity of isoaspartate containing proteins.Structure of MHC class I-like MILL2 reveals heparan-sulfate binding and interdomain flexibility
P2860
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P2860
Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@ast
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@en
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@nl
type
label
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@ast
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@en
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@nl
prefLabel
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@ast
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@en
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@nl
P2093
P50
P1433
P1476
Crystal structures of two H-2D ...... basis for CTL cross-reactivity
@en
P2093
A Glithero
G Arsequell
G Valencia
J S Haurum
P356
10.1016/S1074-7613(00)80007-2
P407
P577
1999-01-01T00:00:00Z