Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazine
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Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experimentsCrystal Structures of the Lumazine Protein from Photobacterium kishitanii in Complexes with the Authentic Chromophore, 6,7-Dimethyl- 8-(1'-D-Ribityl) Lumazine, and Its Analogues, Riboflavin and Flavin Mononucleotide, at High ResolutionCrystallographic and kinetic study of riboflavin synthase fromBrucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibilityVirtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthaseDiscovery and development of a small molecule library with lumazine synthase inhibitory activity.Mechanistic insights on riboflavin synthase inspired by selective binding of the 6,7-dimethyl-8-ribityllumazine exomethylene anionGenetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.Current developments and challenges in the search for a naturally selected Diels-Alderase.O-Nucleoside, S-nucleoside, and N-nucleoside probes of lumazine synthase and riboflavin synthase.A novel lumazine synthase inhibitor derived from oxidation of 1,3,6,8-tetrahydroxy-2,7-naphthyridine to a tetraazaperylenehexaone derivative.(15)N{(31)P} REDOR NMR studies of the binding of phosphonate reaction intermediate analogues to Saccharomyces cerevisiae lumazine synthase.Natural [4 + 2]-Cyclases.Design, synthesis, and biochemical evaluation of 1,5,6,7-tetrahydro-6,7-dioxo-9-D-ribitylaminolumazines bearing alkyl phosphate substituents as inhibitors of lumazine synthase and riboflavin synthase.The C-terminal peptide of Aquifex aeolicus riboflavin synthase directs encapsulation of native and foreign guests by a cage-forming lumazine synthase.Vitamin Biosynthesis as an Antifungal Target.
P2860
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P2860
Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazine
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2002 nî lūn-bûn
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2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@ast
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@en
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@nl
type
label
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@ast
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@en
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@nl
prefLabel
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@ast
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@en
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@nl
P2093
P1433
P1476
Studies on the reaction mechan ...... yethyl-7-oxo-8-ribityllumazine
@en
P2093
Adelbert Bacher
Ann-Kathrin Schott
Boris Illarionov
Mark Cushman
Markus Fischer
Norman Kairies
Robert Huber
Stefan Steinbacher
Wolfgang Eisenreich
P304
P356
10.1016/S0969-2126(02)00864-X
P407
P577
2002-10-01T00:00:00Z