Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif
about
Bidirectional binding of invariant chain peptides to an MHC class II moleculeStructural and Functional Studies of trans -Encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) Protein MoleculeLoss of CD4 T-cell-dependent tolerance to proteins with modified amino acidsUpregulation of the CLIP self peptide on mature dendritic cells antagonizes T helper type 1 polarization.A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approachNaturally occurring altered peptide ligands control Salmonella-specific CD4+ T cell proliferation, IFN-gamma production, and protective potency.Analyses of the specificity of CD4 T cells during the primary immune response to influenza virus reveals dramatic MHC-linked asymmetries in reactivity to individual viral proteins.Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development.Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics.T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity.Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.Divergent motifs but overlapping binding repertoires of six HLA-DQ molecules frequently expressed in the worldwide human population.Self-recognition drives the preferential accumulation of promiscuous CD4(+) T-cells in aged mice.The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.Recognition of open conformers of classical MHC by chaperones and monoclonal antibodies.MHC class II proteins and disease: a structural perspective.Linkers in the structural biology of protein-protein interactionsA hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.Identification of gingipain-specific I-A(b) -restricted CD4+ T cells following mucosal colonization with Porphyromonas gingivalis in C57BL/6 mice.The modulation of adaptive immune responses by bacterial zwitterionic polysaccharides.Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange.High-resolution analysis of the murine MHC class II immunopeptidome.Invariant Chain Complexes and Clusters as Platforms for MIF Signaling.Epitopes rationally selected through computational analyses induce T-cell proliferation in mice and are recognized by serum from individuals infected with Schistosoma mansoni.The MHC Class II Immunopeptidome of Lymph Nodes in Health and in Chemically Induced Colitis.Immune rejection of mouse tumors expressing mutated self.Mapping and restriction of a dominant viral CD4+ T cell core epitope by both MHC class I and MHC class II.The influence of MHC class II molecules containing the rheumatoid arthritis shared epitope on the immune response to aggrecan G1 and its peptides.Contribution of a single hydrogen bond between betaHis81 of MHC class II I-E(k) and the bound peptide to the pH-dependent thermal stability.Antibody specific for the peptide.major histocompatibility complex. Is it T cell receptor-like?Absence of anti-hypocretin receptor 2 autoantibodies in post pandemrix narcolepsy cases.Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.Autoimmunity and tumor immunity induced by immune responses to mutations in self.Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen.The Use of Reverse Vaccinology and Molecular Modeling Associated with Cell Proliferation Stimulation Approach to Select Promiscuous Epitopes from Schistosoma mansoni.The anergy induction of M3 muscarinic acetylcholine receptor-reactive CD4+ T cells suppresses experimental sialadenitis-like Sjögren's syndrome.Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
P2860
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P2860
Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@ast
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@en
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@nl
type
label
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@ast
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@en
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@nl
prefLabel
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@ast
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@en
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@nl
P2093
P1476
Crystal structure of MHC class ...... an I-Ab peptide-binding motif
@en
P2093
Adam L Corper
Alexander Y Rudensky
Luc Teyton
Yuerong Zhu
P304
P356
10.1016/S0022-2836(02)01437-7
P407
P577
2003-02-28T00:00:00Z