Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
about
Structural and functional diversity of the microbial kinomeStructures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activationCloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoformDesign principles underpinning the regulatory diversity of protein kinasesPKA Type II Holoenzyme Reveals a Combinatorial Strategy for Isoform DiversityContribution of Non-catalytic Core Residues to Activity and Regulation in Protein Kinase ARealizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα HoloenzymeStructural Basis for the Regulation of Protein Kinase A by Activation Loop PhosphorylationRole of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein KinaseThe discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug designMolecular Features of Product Release for the PKA Catalytic CycleAddressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of PKA and a PKB MimicDynamics-Driven Allostery in Protein KinasesAtomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor KinasesProtein kinase C: poised to signalIdentifying critical non-catalytic residues that modulate protein kinase A activitycAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometryProtein kinases: evolution of dynamic regulatory proteinsKinetics of acrylodan-labelled cAMP-dependent protein kinase catalytic subunit denaturation.A transition path ensemble study reveals a linchpin role for Mg(2+) during rate-limiting ADP release from protein kinase A.How much NMR data is required to determine a protein-ligand complex structure?Correlated mutation analysis on the catalytic domains of serine/threonine protein kinases.Reciprocally coupled residues crucial for protein kinase Pak2 activity calculated by statistical coupling analysisGlobal consequences of activation loop phosphorylation on protein kinase A.Identifying human kinase-specific protein phosphorylation sites by integrating heterogeneous information from various sourcesThe protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A.Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.Active site inhibitors protect protein kinase C from dephosphorylation and stabilize its mature form.The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module.Phosphoryl Transfer Reaction Snapshots in Crystals: INSIGHTS INTO THE MECHANISM OF PROTEIN KINASE A CATALYTIC SUBUNIT.Demonstration of phosphoryl group transfer indicates that the ATP-binding cassette (ABC) transporter cystic fibrosis transmembrane conductance regulator (CFTR) exhibits adenylate kinase activityMultiple steps to activate FAK's kinase domain: adaptation to confined environments?Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.Eukaryotic-like protein kinases in the prokaryotes and the myxobacterial kinome.Influence of N-myristylation and ligand binding on the flexibility of the catalytic subunit of protein kinase A.Role of conformational entropy in the activity and regulation of the catalytic subunit of protein kinase A.Phosphorylation releases constraints to domain motion in ERK2.Protein kinase C pharmacology: refining the toolbox.Identification of functionally distinct regions that mediate biological activity of the protein kinase a homolog Tpk2.Understanding how cAMP-dependent protein kinase can catalyze phosphoryl transfer in the presence of Ca2+ and Sr2+: a QM/MM study.
P2860
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P2860
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@ast
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@en
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@nl
type
label
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@ast
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@en
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@nl
prefLabel
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@ast
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@en
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@nl
P2093
P3181
P1476
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
@en
P2093
Lynn F Ten Eyck
Madhusudan
Nguyen-Huu Xuong
Pearl Akamine
Susan S Taylor
P304
P3181
P356
10.1016/S0022-2836(02)01446-8
P407
P577
2003-03-14T00:00:00Z