Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins
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A historical perspective on protein crystallization from 1840 to the present dayDetermination of protein structures--a series of fortunate events.Simple Host−Guest Chemistry To Modulate the Process of Concentration and Crystallization of Membrane Proteins by Detergent Capture in a Microfluidic DeviceThe plug-based nanovolume Microcapillary Protein Crystallization System (MPCS)Structural and spectropotentiometric analysis of Blastochloris viridis heterodimer mutant reaction centerUser-loaded SlipChip for equipment-free multiplexed nanoliter-scale experimentsMultiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods.Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM DomainNew insights into the structure of the reaction centre from Blastochloris viridis: evolution in the laboratoryUnmet challenges of structural genomicsAcoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines.Single-cell analysis and sorting using droplet-based microfluidicsThe chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution.SlipChipEvolution of catalysts directed by genetic algorithms in a plug-based microfluidic device tested with oxidation of methane by oxygen.Microfluidic device for robust generation of two-component liquid-in-air slugs with individually controlled composition.High-throughput injection with microfluidics using picoinjectors.Surface modification of droplet polymeric microfluidic devices for the stable and continuous generation of aqueous droplets.A new microfluidics-based droplet dispenser for ICPMSCapture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.Towards combinatorial mixing devices without any pumps by open-capillary channels: fundamentals and applicationsCarboxylate shifts steer interquinone electron transfer in photosynthesis.A Plug-Based Microfluidic System for Dispensing Lipidic Cubic Phase (LCP) Material Validated by Crystallizing Membrane Proteins in Lipidic Mesophases.Coalescence-assisted generation of single nanoliter droplets with predefined composition.A Stochastic Model for Nucleation Kinetics Determination in Droplet-Based Microfluidic Systems.Automated generation of libraries of nL droplets.Overcoming the challenges of membrane protein crystallography.Salvage and storage of infectious disease protein targets in the SSGCID high-throughput crystallization pathway using microfluidics.Nanovolume optimization of protein crystal growth using the microcapillary protein crystallization system.Using three-phase flow of immiscible liquids to prevent coalescence of droplets in microfluidic channels: criteria to identify the third liquid and validation with protein crystallizationHigh-Throughput Single-Cell Cultivation on Microfluidic Streak Plates.A serial sample loading system: interfacing multiwell plates with microfluidic devices.Microfluidics for drug discovery and development: from target selection to product lifecycle management.Cryocrystallography in capillaries: critical glycerol concentrations and cooling ratesPlug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides.Measuring the nucleation rate of Lysozyme using microfluidics.Isolation, incubation, and parallel functional testing and identification by FISH of rare microbial single-copy cells from multi-species mixtures using the combination of chemistrode and stochastic confinementTopology of class A G protein-coupled receptors: insights gained from crystal structures of rhodopsins, adrenergic and adenosine receptorsCyclic olefin homopolymer-based microfluidics for protein crystallization and in situ X-ray diffraction.Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination.
P2860
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P2860
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@ast
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@en
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@nl
type
label
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@ast
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@en
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@nl
prefLabel
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@ast
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@en
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@nl
P2093
P2860
P356
P1476
Nanoliter microfluidic hybrid ...... llization of membrane proteins
@en
P2093
Debarshi Mustafi
Delai L Chen
Joshua D Tice
Rustem F Ismagilov
P2860
P304
P356
10.1073/PNAS.0607502103
P407
P577
2006-12-19T00:00:00Z