Sanglifehrin-cyclophilin interaction: degradation work, synthetic macrocyclic analogues, X-ray crystal structure, and binding data
about
Efficient trapping of HIV-1 envelope protein by hetero-oligomerization with an N-helix chimera.Primary Identification, Biochemical Characterization, and Immunologic Properties of the Allergenic Pollen Cyclophilin Cat r 1The overlap of small molecule and protein binding sites within families of protein structuresTranslation of DNA into a library of 13,000 synthetic small-molecule macrocycles suitable for in vitro selection.The cyclophilin-binding agent Sanglifehrin A is a dendritic cell chemokine and migration inhibitorBioengineering and semisynthesis of an optimized cyclophilin inhibitor for treatment of chronic viral infection.A high-throughput screen for inhibitors of the prolyl isomerase, Pin1, identifies a seaweed polyphenol that reduces adipose cell differentiation.Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization.Piperazic acid-containing natural products: isolation, biological relevance and total synthesis.Synthesis and structure-activity relationship study of FD-891: importance of the side chain and C8-C9 epoxide for cytotoxic activity against cancer cells.Natural product analogues: towards a blueprint for analogue-focused synthesis.Preclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family.Immunosuppressive activity of the immunophilin-binding drug Sanglifehrin A in human whole blood: potent inhibition of interleukin-6 produced by lymphocytes and monocytes.Cyclophilin sensitivity to sanglifehrin A can be correlated to the same specific tryptophan residue as cyclosporin A.Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6 A resolution.Novel cyclophilin D inhibitors derived from quinoxaline exhibit highly inhibitory activity against rat mitochondrial swelling and Ca2+ uptake/ release.Peptidylprolyl Isomerases as In Vivo Carriers for Drugs That Target Various Intracellular Entities.Total Synthesis of Two Possible Diastereomers of Natural 6-Chlorotetrahydrofuran Acetogenin and Its Stereostructural Elucidation.
P2860
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P2860
Sanglifehrin-cyclophilin interaction: degradation work, synthetic macrocyclic analogues, X-ray crystal structure, and binding data
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@ast
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@en
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@nl
type
label
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@ast
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@en
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@nl
prefLabel
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@ast
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@en
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@nl
P2093
P356
P1476
Sanglifehrin-cyclophilin inter ...... al structure, and binding data
@en
P2093
Anne-Marie Jutzi Eme
Charles D Papageorgiou
Dieter Wagner
Francesco Senia
Gerhard Zenke
Grety Rihs
Julien France
Jörg Kallen
Jürgen Wagner
P304
P356
10.1021/JA021327Y
P407
P577
2003-04-02T00:00:00Z