Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal
about
Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid bindingSize matters in activation/inhibition of ligand-gated ion channelsPartial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) Forms an Irreversible Bond To the Active Site of the GluR2 AMPA Receptor †Structure of the S1S2 glutamate binding domain of GLuR3Correlating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists †Mechanisms of Antagonism of the GluR2 AMPA Receptor: Structure and Dynamics of the Complex of Two Willardiine Antagonists with the Glutamate Binding DomainMechanisms of Modal Activation of GluA3 ReceptorsMechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONSThermodynamics and Mechanism of the Interaction of Willardiine Partial Agonists with a Glutamate Receptor: Implications for Drug DevelopmentGlutamate receptor ion channels: structure, regulation, and functionInfluence of a threonine residue in the S2 ligand binding domain in determining agonist potency and deactivation rate of recombinant NR1a/NR2D NMDA receptorsDomain architecture of a calcium-permeable AMPA receptor in a ligand-free conformation.AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins.Energetics of the cleft closing transition and the role of electrostatic interactions in conformational rearrangements of the glutamate receptor ligand binding domain.Glutamate receptors as seen by light: spectroscopic studies of structure-function relationships.Energy transfer ligands of the GluR2 ligand binding coreStructure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acidStructural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2.The relationship between agonist potency and AMPA receptor kinetics.Characterizing single-channel behavior of GluA3 receptorsChannel-opening kinetic mechanism of wild-type GluK1 kainate receptors and a C-terminal mutant.The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors.Chemical interplay in the mechanism of partial agonist activation in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 ReceptorsMechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution.Dynamics of the Ligand Binding Domain Layer during AMPA Receptor Activation.NMR spectroscopy of the ligand-binding core of ionotropic glutamate receptor 2 bound to 5-substituted willardiine partial agonists.A quantum biochemistry investigation of willardiine partial agonism in AMPA receptors.Computational Investigation into the Interactions of Traditional Chinese Medicine Molecules of WenQingYin with GluR2Rigid body essential X-ray crystallography: distinguishing the bend and twist of glutamate receptor ligand binding domains.Quantifying water-mediated protein-ligand interactions in a glutamate receptor: a DFT study.Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate.Solution X-ray scattering evidence for agonist- and antagonist-induced modulation of cleft closure in a glutamate receptor ligand-binding domain.
P2860
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P2860
Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@ast
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@en
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@nl
type
label
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@ast
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@en
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@nl
prefLabel
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@ast
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@en
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@nl
P356
P1433
P1476
Probing the function, conforma ...... and GluR2 S1S2 in the crystal
@en
P304
P356
10.1021/BI020632T
P407
P577
2003-05-13T00:00:00Z