Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
about
Synapsis of loxP sites by Cre recombinaseInaugural structure from the DUF3349 superfamily of proteins, Mycobacterium tuberculosis Rv0543cStructural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bendingA genetic assay for transcription errors reveals multilayer control of RNA polymerase II fidelityFunctional mapping of Cre recombinase by pentapeptide insertional mutagenesis.A Cre Transcription Fidelity Reporter Identifies GreA as a Major RNA Proofreading Factor in Escherichia coli.Multiple levels of affinity-dependent DNA discrimination in Cre-LoxP recombination.Reversed DNA strand cleavage specificity in initiation of Cre-LoxP recombination induced by the His289Ala active-site substitutionSingle molecule TPM analysis of the catalytic pentad mutants of Cre and Flp site-specific recombinases: contributions of the pentad residues to the pre-chemical steps of recombinationProtein-induced local DNA bends regulate global topology of recombination productsReal-time single-molecule tethered particle motion experiments reveal the kinetics and mechanisms of Cre-mediated site-specific recombination.Measurements of DNA-loop formation via Cre-mediated recombination.Capturing reaction paths and intermediates in Cre-loxP recombination using single-molecule fluorescenceReal-time single-molecule tethered particle motion analysis reveals mechanistic similarities and contrasts of Flp site-specific recombinase with Cre and λ IntDiscovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineeringPeptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.Insights into the preferential order of strand exchange in the Cre/loxP recombinase system: impact of the DNA spacer flanking sequence and flexibility.Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach.Intein-mediated Cre protein assembly for transgene excision in hybrid progeny of transgenic Arabidopsis.Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.Preferential synapsis of loxP sites drives ordered strand exchange in Cre-loxP site-specific recombination.
P2860
Q27645952-4300DD05-D154-4137-B12A-0865FEE0206EQ27666231-BFED9039-AF10-423D-96A4-8AFBAC1297EEQ28468564-C0BDDFEB-DB70-48B1-A208-48C4D07E42F1Q28543050-F9DB7C83-EB8D-4537-90AD-150B020D5FD4Q33204212-BF54066A-6502-48A7-AC1B-565A4F48A862Q33642780-6A812FD8-76F9-4605-B8E7-7BDF45D037EEQ33938573-A399F448-29CB-4B48-A45D-1C6BFCD520C3Q34240909-F1E228BB-7A5B-4F62-9616-8363738C1D0EQ35237033-281DDFD7-45BA-43EA-B483-091B972E5EAAQ35933659-1B566660-9277-4799-B685-6F6061BE4D6DQ36106954-9C34584E-0399-408B-8A16-0932B5336FA3Q36180260-07D12573-E551-439E-9F6A-B210006DE15FQ36485115-93278EF5-988A-4C10-95B7-3E22A882B8F6Q37080351-80673C86-FEF8-41A0-AB6C-FC104C30DDC3Q37117468-A3D1853B-61C6-4934-8B38-3C0B0D9D8D27Q38333282-2E65DDD0-C277-46A2-AE33-4ACB3DCC3DB9Q39979692-7D116525-6DC5-4A34-8800-A1363B253480Q41629853-315D747B-3B30-41E4-B2D2-739F49BC6A48Q41835073-786CDAF0-F898-4955-9939-1956068FFE69Q50795073-AC55F37D-35C1-446A-9E86-45FF6C18FDFDQ52351418-4839FC9F-3437-4942-AD4C-43C98CDAA586Q53641062-F82A258A-4C2D-442F-A678-F138BCAF4A44
P2860
Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@ast
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@en
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@nl
type
label
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@ast
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@en
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@nl
prefLabel
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@ast
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@en
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of a wild-ty ...... sm for DNA cleavage activation
@en
P2093
A Francis Stewart
Eric Ennifar
Joachim E W Meyer
P2860
P304
P3181
P356
10.1093/NAR/GKG732
P407
P577
2003-09-15T00:00:00Z