Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex
about
A host-guest approach for determining drug-DNA interactions: an example using netropsinStructures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutationsMinor groove binding of a bis-quaternary ammonium compound: the crystal structure of SN 7167 bound to d(CGCGAATTCGCG)2Significance of ligand tails for interaction with the minor groove of B-DNAMethylation of the nucleobases in RNA oligonucleotides mediates duplex-hairpin conversion.Analysis of local helix bending in crystal structures of DNA oligonucleotides and DNA-protein complexes.Knowledge-based elastic potentials for docking drugs or proteins with nucleic acidsGenome-Targeted Drug Design: Understanding the Netropsin-DNA InteractionEvidence from in vitro replication that O6-methylguanine can adopt multiple conformationsDiastereoselective DNA cleavage recognition by Ni(II) x Gly-Gly-His-derived metallopeptidesTranscription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymeraseSensitivities to parameterization in the size-modified Poisson-Boltzmann equation.Exocyclic groups in the minor groove influence the backbone conformation of DNA.Hydrogen bond geometry in DNA-minor groove binding drug complexesStructure of the hydrogen bonding complex of O6-methylguanine with cytosine and thymine during DNA replication.Break in the heat capacity change at 303 K for complex binding of netropsin to AATT containing hairpin DNA constructs.
P2860
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P2860
Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex
description
1992 nî lūn-bûn
@nan
1992 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年學術文章
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name
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@ast
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@en
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@nl
type
label
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@ast
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@en
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@nl
prefLabel
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@ast
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@en
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@nl
P2093
P1433
P1476
Structural consequences of a c ...... 6G]AATTCGCG)-netropsin complex
@en
P2093
G A van der Marel
H L Roelen
J H van Boom
P304
P407
P577
1992-12-01T00:00:00Z