Structure of apo, unactivated insulin-like growth factor-1 receptor kinase at 1.5 A resolution
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Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane regionSmall-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptorCrystal structure of the ALK (anaplastic lymphoma kinase) catalytic domainA Highly Selective Dual Insulin Receptor (IR)/Insulin-like Growth Factor 1 Receptor (IGF-1R) Inhibitor Derived from an Extracellular Signal-regulated Kinase (ERK) InhibitorStructural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase InhibitorsThe "Sticky Patch" Model of Crystallization and Modification of Proteins for Enhanced Crystallizability.RILM: a web-based resource to aid comparative and functional analysis of the insulin and IGF-1 receptor family.The crystal structure of the reduced, Zn2+-bound form of the B. subtilis Hsp33 chaperone and its implications for the activation mechanism.Application of protein engineering to enhance crystallizability and improve crystal properties.Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution.The structure and ligand binding properties of the B. subtilis YkoF gene product, a member of a novel family of thiamin/HMP-binding proteins.Toward rational protein crystallization: A Web server for the design of crystallizable protein variants.Protein crystallization in drug design: towards a rational approach.Synthesis of aryl-heteroaryl ureas (AHUs) based on 4-aminoquinoline and their evaluation against the insulin-like growth factor receptor (IGF-1R).Dynamic, structural and thermodynamic basis of insulin-like growth factor 1 kinase allostery mediated by activation loop phosphorylation.Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineeringTrading the micro-world of combinatorial complexity for the macro-world of protein interaction domains.SCMCRYS: predicting protein crystallization using an ensemble scoring card method with estimating propensity scores of P-collocated amino acid pairs.Improvement of the crystallizability and expression of an RNA crystallization chaperoneHow IGF-1 activates its receptor.Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage DifferentiationSystematic replacement of lysine with glutamine and alanine in Escherichia coli malate synthase G: effect on crystallization.Serine phosphorylation of the insulin-like growth factor I (IGF-1) receptor C-terminal tail restrains kinase activity and cell growthIGF-1 receptor inhibitors in clinical trials--early lessonsAugmentation of response to nab-paclitaxel by inhibition of insulin-like growth factor (IGF) signaling in preclinical pancreatic cancer models.The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer.Allosteric IGF-1R Inhibitors.Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation.Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.Expression and purification of functional insulin and insulin-like growth factor 1 holoreceptors from mammalian cells.
P2860
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P2860
Structure of apo, unactivated insulin-like growth factor-1 receptor kinase at 1.5 A resolution
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@ast
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@en
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@nl
type
label
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@ast
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@en
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@nl
prefLabel
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@ast
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@en
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@nl
P2093
P3181
P1476
Structure of apo, unactivated ...... tor kinase at 1.5 A resolution
@en
P2093
Dawn L Hall
Lawrence C Kuo
Maria Kornienko
Paul L Darke
Sanjeev Munshi
P304
P3181
P356
10.1107/S0907444903015415
P577
2003-10-01T00:00:00Z