High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide
about
Insights into the Reaction of Protein-tyrosine Phosphatase 1B: CRYSTAL STRUCTURES FOR TRANSITION STATE ANALOGS OF BOTH CATALYTIC STEPSUtilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase ‡Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of theYersinia pestisprotein tyrosine phosphatase YopHStructure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognitionA rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopH.NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH.Derivatives of salicylic acid as inhibitors of YopH in Yersinia pestisOxime-based click chemistry in the development of 3-isoxazolecarboxylic acid containing inhibitors of Yersinia pestis protein tyrosine phosphatase, YopH.Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors.Biomolecular Interactions of small-molecule inhibitors affecting the YopH protein tyrosine phosphatase.Analysis of protein tyrosine phosphatase interactions with microarrayed phosphopeptide substrates using imaging mass spectrometryPositional effects of fusion partners on the yield and solubility of MBP fusion proteins.Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches.A highly efficient route to enantiomerically pure l-N-Bz-Pmp(t-Bu)2-OH and incorporation into a peptide-based protein tyrosine phosphatase inhibitorYersinia outer proteins: Yops.Yersinia pestis: mechanisms of entry into and resistance to the host cell.Docking flexible peptide to flexible protein by molecular dynamics using two implicit-solvent models: an evaluation in protein kinase and phosphatase systems.Protein tyrosine phosphatase structure-function relationships in regulation and pathogenesis.Structural insight into effector proteins of Gram-negative bacterial pathogens that modulate the phosphoproteome of their host.Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH.
P2860
Q27660261-0D256A3B-3352-461E-BA05-C9080728B6ECQ27667338-5B7CBC3A-FB69-4868-9FD3-B0D4AFCCB4BFQ27670522-EE7A697F-BD98-42B4-B505-D95FAC4DA458Q27675796-B76E2B62-7EBC-4AAD-A29B-315A380DC62EQ33547251-128CEA34-7B6F-4535-8447-40A73794068AQ33574016-439EEC9A-F8C9-44DA-80BB-631B2018E6ADQ33609113-B5B1B217-5BC6-4F1B-B93E-4140FF1253B7Q33931893-E894A28E-CD67-4DB6-A232-D5DD9C6E7F87Q34197585-824F9CEC-AD38-4F19-925D-DE2119E83A65Q34513199-98167251-1C6B-433D-9D8D-C862B2FEF667Q34887821-D2CFC174-C0B5-4449-A76A-268C9268BCEBQ35371470-D0C56898-F85F-41CF-8931-D48C5764ED0CQ36403197-F4F55C50-CA34-4D76-BCF5-2DB96269734BQ36584010-A9C123DC-E817-4F61-98C6-0B305C622C74Q36645535-D1BD0B5D-E31D-4D58-ABB5-3CD8AA39E8FFQ37032798-18522ADE-EBED-46D5-B614-B2EB478A3D33Q37412102-3F3064A8-0079-4430-B98B-3D966C7D753FQ37445757-C411C4C2-05FC-4DC8-B618-D85CBB9DA052Q38017355-8F1D5616-5F37-41AE-8DC3-310019E14AABQ38309987-6229DF38-F571-4EDE-84B9-086C6017ADEFQ41431195-73B9FE57-1689-494C-89E3-07695C5F7BF1
P2860
High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
High-resolution structure of t ...... mimetic-containing hexapeptide
@ast
High-resolution structure of t ...... mimetic-containing hexapeptide
@en
High-resolution structure of t ...... mimetic-containing hexapeptide
@nl
type
label
High-resolution structure of t ...... mimetic-containing hexapeptide
@ast
High-resolution structure of t ...... mimetic-containing hexapeptide
@en
High-resolution structure of t ...... mimetic-containing hexapeptide
@nl
prefLabel
High-resolution structure of t ...... mimetic-containing hexapeptide
@ast
High-resolution structure of t ...... mimetic-containing hexapeptide
@en
High-resolution structure of t ...... mimetic-containing hexapeptide
@nl
P2093
P356
P1433
P1476
High-resolution structure of t ...... mimetic-containing hexapeptide
@en
P2093
David S Waugh
Jason Phan
Joseph E Tropea
Kyeong Lee
Scott Cherry
Terrence R Burke
P304
P356
10.1021/BI030156M
P407
P577
2003-11-18T00:00:00Z