DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
about
PTOP interacts with POT1 and regulates its localization to telomeresPOT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substratesHSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage responsePOT1 and TRF2 cooperate to maintain telomeric integrityFinding the end: recruitment of telomerase to telomeresTelomeres-structure, function, and regulationSingle-stranded DNA-binding proteins: multiple domains for multiple functionsRecognition of DNA substrates by T4 bacteriophage polynucleotide kinaseStn1-Ten1 is an Rpa2-Rpa3-like complex at telomeresHow telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNACrystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complexCdc13 N-Terminal Dimerization, DNA Binding, and Telomere Length RegulationStructural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase αA conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organismsCdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere MaintenanceStructural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNASua5p a single-stranded telomeric DNA-binding protein facilitates telomere replicationBinding and activation of DNA topoisomerase III by the Rmi1 subunit.Genetic analysis reveals essential and non-essential amino acids within the telomeric DNA-binding interface of Cdc13p.Telomere DNA recognition in Saccharomycotina yeast: potential lessons for the co-evolution of ssDNA and dsDNA-binding proteins and their target sitesTelomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1Switching human telomerase on and off with hPOT1 protein in vitroOligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardiansStructure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protectionPOT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombinationEvolution of Arabidopsis protection of telomeres 1 alters nucleic acid recognition and telomerase regulationNABP1, a novel RORgamma-regulated gene encoding a single-stranded nucleic-acid-binding proteinDivergent evolution within protein superfolds inferred from profile-based phylogeneticsDNA binding affinity and sequence permutation preference of the telomere protein from Euplotes crassus.DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombeThermodynamic characterization of binding Oxytricha nova single strand telomere DNA with the alpha protein N-terminal domain.Cell cycle localization, dimerization, and binding domain architecture of the telomere protein cPot1.Distinct requirements for Pot1 in limiting telomere length and maintaining chromosome stabilityThe Arabidopsis Pot1 and Pot2 proteins function in telomere length homeostasis and chromosome end protectionAlterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha.Identification of the determinants for the specific recognition of single-strand telomeric DNA by Cdc13Vertebrate POT1 restricts G-overhang length and prevents activation of a telomeric DNA damage checkpoint but is dispensable for overhang protectionProtection of telomeres by a conserved Stn1-Ten1 complex.Deciphering the mechanism of thermodynamic accommodation of telomeric oligonucleotide sequences by the Schizosaccharomyces pombe protection of telomeres 1 (Pot1pN) protein.Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita
P2860
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P2860
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@ast
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@en
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@nl
type
label
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@ast
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@en
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@nl
prefLabel
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@ast
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@en
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@nl
P50
P3181
P356
P1433
P1476
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
@en
P2093
P2888
P304
P3181
P356
10.1038/NATURE02092
P407
P577
2003-11-13T00:00:00Z
P6179
1043051012