Crystal structure of scallop Myosin s1 in the pre-power stroke state to 2.6 a resolution: flexibility and function in the head
about
The closed MTIP-myosin A-tail complex from the malaria parasite invasion machineryPoorly understood aspects of striated muscle contractionAn Unstable Head–Rod Junction May Promote Folding into the Compact Off-State Conformation of Regulated MyosinsVisualizing key hinges and a potential major source of compliance in the lever arm of myosinCan morphing methods predict intermediate structures?Fast adaptation in vestibular hair cells requires myosin-1c activity.Conservation of the regulated structure of folded myosin 2 in species separated by at least 600 million years of independent evolutionUnidirectional Brownian motion observed in an in silico single molecule experiment of an actomyosin motor.Structural basis of the relaxed state of a Ca2+-regulated myosin filament and its evolutionary implications.Structure of actomyosin rigour complex at 5.2 Å resolution and insights into the ATPase cycle mechanismMapping interactions between myosin relay and converter domains that power muscle function.Axial and radial forces of cross-bridges depend on lattice spacing.Coarse-Grained Structural Modeling of Molecular Motors Using Multibody Dynamics.Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight abilityMyosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.Switch I closure simultaneously promotes strong binding to actin and ADP in smooth muscle myosin.Coupling of lever arm swing and biased Brownian motion in actomyosin.Disrupting the myosin converter-relay interface impairs Drosophila indirect flight muscle performanceMyosin S2 origins track evolution of strong binding on actin by azimuthal rolling of motor domain.Optimized torsion-angle normal modes reproduce conformational changes more accurately than cartesian modes.Three distinct actin-attached structural states of myosin in muscle fibers.Structure and Regulation of the Movement of Human Myosin VIIA.Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness.Modification of interface between regulatory and essential light chains hampers phosphorylation-dependent activation of smooth muscle myosin3-D structural analysis of the crucial intermediate of skeletal muscle myosin and its role in revised actomyosin cross-bridge cycle.Predicting allosteric communication in myosin via a pathway of conserved residues.A Failure to Communicate: MYOSIN RESIDUES INVOLVED IN HYPERTROPHIC CARDIOMYOPATHY AFFECT INTER-DOMAIN INTERACTION.Purification, crystallization and preliminary X-ray crystallographic analysis of squid heavy meromyosinMammalian myosin-18A, a highly divergent myosin.Force-producing ADP state of myosin bound to actin.Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function.Structural basis for drug-induced allosteric changes to human β-cardiac myosin motor activityInvertebrate muscles: thin and thick filament structure; molecular basis of contraction and its regulation, catch and asynchronous muscle.Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil.Orientation of the N- and C-terminal lobes of the myosin regulatory light chain in cardiac muscle.Actomyosin interaction: mechanical and energetic properties in different nucleotide binding states.Flexibility within the heads of muscle myosin-2 molecules.Calcium-mediated regulation of recombinant hybrids of full-length Physarum myosin heavy chain with Physarum/scallop myosin light chainsTransgenic expression and purification of myosin isoforms using the Drosophila melanogaster indirect flight muscle system.The structure of the actin-smooth muscle myosin motor domain complex in the rigor state.
P2860
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P2860
Crystal structure of scallop Myosin s1 in the pre-power stroke state to 2.6 a resolution: flexibility and function in the head
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of scallop M ...... ility and function in the head
@ast
Crystal structure of scallop M ...... ility and function in the head
@en
Crystal structure of scallop M ...... ility and function in the head
@nl
type
label
Crystal structure of scallop M ...... ility and function in the head
@ast
Crystal structure of scallop M ...... ility and function in the head
@en
Crystal structure of scallop M ...... ility and function in the head
@nl
prefLabel
Crystal structure of scallop M ...... ility and function in the head
@ast
Crystal structure of scallop M ...... ility and function in the head
@en
Crystal structure of scallop M ...... ility and function in the head
@nl
P2093
P1433
P1476
Crystal structure of scallop M ...... ility and function in the head
@en
P2093
Andrew G Szent-Györgyi
Daniel M Himmel
Jerry H Brown
Ludmilla Reshetnikova
S Gourinath
P304
P577
2003-12-01T00:00:00Z