The APOBEC-2 crystal structure and functional implications for the deaminase AID
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Model structure of human APOBEC3GAID and APOBECs span the gap between innate and adaptive immunityDeaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminaseStructure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activitiesCrystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfacesStructural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3GHIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factorsHuman LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activityRegulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombinationAn extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme modelCrystal structure of the anti-viral APOBEC3G catalytic domain and functional implicationsStructure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3GA single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivityIdentification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidationNew Insights into the Biological Role of Mammalian ADARs; the RNA Editing ProteinsMultiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them allA Cytidine Deaminase Edits C to U in Transfer RNAs in ArchaeaCrystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding DomainThe APOBEC3C crystal structure and the interface for HIV-1 Vif bindingThe structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal StructureRNA Editing-Systemic Relevance and Clue to Disease Mechanisms?RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1APOBEC3G: an intracellular centurionCitrulline Supplementation Induces Changes in Body Composition and Limits Age-Related Metabolic Changes in Healthy Male Rats.AID and Apobec3G haphazard deamination and mutational diversityFree Energy Profile of APOBEC3G Protein Calculated by a Molecular Dynamics SimulationReduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities.Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA.Transfer RNA processing in archaea: unusual pathways and enzymesProximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2.Functions and regulation of the APOBEC family of proteinsRationalisation of the differences between APOBEC3G structures from crystallography and NMR studies by molecular dynamics simulationsDeficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy.Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics.Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulationDNA methylation is associated with altered gene expression in AMD.High-throughput mutagenesis reveals functional determinants for DNA targeting by activation-induced deaminase.A Proteome-wide Domain-centric Perspective on Protein Phosphorylation.Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.
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P2860
The APOBEC-2 crystal structure and functional implications for the deaminase AID
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2007 nî lūn-bûn
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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2007 թվականի հունվարին հրատարակված գիտական հոդված
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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name
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@ast
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@en
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@nl
type
label
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@ast
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@en
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@nl
prefLabel
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@ast
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@en
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@nl
P2093
P921
P3181
P356
P1433
P1476
The APOBEC-2 crystal structure and functional implications for the deaminase AID
@en
P2093
Courtney Prochnow
Michael G Klein
Myron F Goodman
Ronda Bransteitter
Xiaojiang S Chen
P2888
P304
P3181
P356
10.1038/NATURE05492
P407
P577
2007-01-25T00:00:00Z
P5875
P6179
1027131449