Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
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Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolismStructure of isochorismate synthase in complex with magnesiumLigand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzEStructure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complexThe promoter of Rv0560c is induced by salicylate and structurally-related compounds in Mycobacterium tuberculosisMechanistic analysis of Mycobacterium tuberculosis Rv1347c, a lysine Nepsilon-acyltransferase involved in mycobactin biosynthesisAn Open and Shut Case: The Interaction of Magnesium with MST EnzymesBiochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosisInhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening.Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.Pericyclic reactions catalyzed by chorismate-utilizing enzymes.Breaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategyThe TB Structural Genomics Consortium: a decade of progress.Stereocontrolled Synthesis of a Potential Transition-State Inhibitor of the Salicylate Synthase MbtI from Mycobacterium tuberculosis.Small molecule inhibition of microbial natural product biosynthesis-an emerging antibiotic strategy.Lysine221 is the general base residue of the isochorismate synthase from Pseudomonas aeruginosa (PchA) in a reaction that is diffusion limited.Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities.Biosynthesis of mycobacterial lipids by polyketide synthases and beyond.Development of new antituberculous agents based on new drug targets and structure-activity relationship.Conversion of anthranilate synthase into isochorismate synthase: implications for the evolution of chorismate-utilizing enzymes.A new salicylate synthase AmS is identified for siderophores biosynthesis in Amycolatopsis methanolica 239(T).Comparative studies of the catalytic mechanisms of two chorismatases: CH-fkbo and CH-Hyg5.Synthesis of Transition-State Inhibitors of Chorismate Utilizing Enzymes from Bromobenzene cis-1,2-Dihydrodiol.Biocatalytic Potential of Enzymes Involved in the Biosynthesis of Isoprenoid Quinones
P2860
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P2860
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@ast
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@en
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@nl
type
label
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@ast
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@en
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@nl
prefLabel
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@ast
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@en
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@nl
P2093
P3181
P356
P1433
P1476
Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
@en
P2093
Jacque Zwahlen
Subramaniapillai Kolappan
P304
P3181
P356
10.1021/BI060852X
P407
P577
2007-01-30T00:00:00Z